[HTML][HTML] What can the common fruit fly teach us about stroke?: lessons learned from the hypoxic tolerant Drosophila melanogaster

PS Quadros-Mennella, KM Lucin… - Frontiers in Cellular …, 2024 - frontiersin.org
Stroke, resulting in hypoxia and glucose deprivation, is a leading cause of death and
disability worldwide. Presently, there are no treatments that reduce neuronal damage and …

Neural processing without O2 and glucose delivery: from the pond to the clinic

L do Amaral Silva, JM Santin - Physiology, 2024 - journals.physiology.org
Neuronal activity requires a large amount of ATP, leading to a rapid collapse of brain
function when aerobic respiration fails. Here, we summarize how rhythmic motor circuits in …

[HTML][HTML] Synaptic modifications transform neural networks to function without oxygen

L Amaral-Silva, JM Santin - BMC biology, 2023 - Springer
Background Neural circuit function is highly sensitive to energetic limitations. Much like
mammals, brain activity in American bullfrogs quickly fails in hypoxia. However, after …

[HTML][HTML] Bioinformatic analysis and clinical diagnostic value of hsa_circ_0004099 in acute ischemic stroke

J Zheng, S Luo, Y Long - PLoS One, 2022 - journals.plos.org
This study investigates the expression and effect of hsa_circ_0004099 in acute ischemic
stroke (AIS). We conducted a case-controlled study that included 40 patients with AIS within …

Cellular and molecular targets in acute ischemic stroke

P Kraft, MK Schuhmann - International Journal of Molecular Sciences, 2022 - mdpi.com
Despite the available treatment strategies, ischemic stroke (IS) is still a leading cause of
death and disability worldwide. Therefore, novel cellular and molecular targets for potential …