Paxlovid (nirmatrelvir/ritonavir) effectiveness against hospitalization and death in N3C: A target trial emulation study

K Hansen, SR Makkar, D Sahner, J Fessel, N Hotaling… - medRxiv, 2023 - medrxiv.org
Importance COVID-19 has placed a monumental burden on the health care system globally.
Although no longer a public health emergency, there is still a pressing need for effective …

Development of a prediction model for 30-day COVID-19 hospitalization and death in a national cohort of Veterans Health Administration patients-March 2022-April …

DP Bui, KL Bajema, Y Huang, L Yan, Y Li, N Rajeevan… - medRxiv, 2023 - medrxiv.org
Objective: Develop models to predict 30-day COVID-19 hospitalization and death in the
Omicron era for clinical and research applications. Material and Methods: We used …

[HTML][HTML] Effectiveness of Molnupiravir Treatment in Patients with COVID-19 in Korea: A Propensity Score Matched Study

HR Park, MG Yoo, JM Kim, SJ Bae, H Lee… - Infection & …, 2023 - ncbi.nlm.nih.gov
Background The MOVe-OUT (efficacy and safety of molnupiravir [MK-4482] in non-
hospitalized adult participants with COVID-19 [MK-4482-002]) trial reported that the …

Oral COVID-19 antiviral uptake among a highly vaccinated US cohort of adults with SARS-CoV-2 infection between December 2021 and October 2022

Y Shen, MKM Robertson, SG Kulkarni… - Open Forum …, 2024 - academic.oup.com
Background We described the oral nirmatrelvir/ritonavir (NMV/r) and molnupiravir (MOV)
uptake among a subgroup of highly vaccinated adults in a US national prospective cohort …

Molnupiravir's real-world effectiveness in COVID-19 outpatients at high risk of severe disease: a single-center study

II Gmizic, A Barac, N Todorovic, M Sabanovic… - The Journal of Infection …, 2024 - jidc.org
Introduction: The coronavirus disease 2019 (COVID-19) pandemic started in March 2020.
Since then, there has been an urgent need for effective therapeutic methods to manage the …

Role of Molnupiravir in the Treatment of COVID-19

A Sharma, VM Patil, M Dahiya, GP Singh… - Anti-Infective …, 2023 - ingentaconnect.com
Background: Molnupiravir is a ribonucleoside analog and exhibits its antiviral mechanism by
inhibiting replication. Preclinical studies have been reported that support the role of …

COVID-19 infection: antiviral therapy

H Öztürk, M Özsoy - Intercontinental Journal of Internal Medicine, 2024 - journal-icjim.com
This review summarizes the current literature on antiviral drugs used in the treatment of
COVID-19. The pandemic caused by COVID-19 is an important cause of mortality and …

Real-life comparison of mortality in patients with SARS-CoV-2 infection at risk for clinical progression treated with molnupiravir or nirmatrelvir plus ritonavir during the …

C Torti, PP Olimpieri, P Bonfanti, C Tascini… - The Lancet Regional …, 2023 - thelancet.com
Background Comparative data on mortality in COVID-19 patients treated with molnupiravir
or with nirmatrelvir plus ritonavir are inconclusive. We therefore compared all-cause …

[HTML][HTML] COVID-19: An Update on Epidemiology, Prevention and Treatment, September-2023

S Şimşek-Yavuz - Infectious Diseases & Clinical Microbiology, 2023 - ncbi.nlm.nih.gov
After a downward trend for more than 12 months, the incidence of COVID-19 has increased
in the last months. Although COVID-19 is not as frequent as in the first years of the …

Molnupiravir's real-world effectiveness in COVID-19 non-hospitalized patients at high risk of severe disease: a single-center study

I Gmizic, N Todorovic, M Sabanovic, N Kekic… - medRxiv, 2023 - medrxiv.org
Objective To assess the real-world effectiveness of molnupiravir (MOL) in reducing the need
for hospitalization in at-risk, non-hospitalized patients with confirmed COVID-19. Methods A …