SARS-CoV-2-specific immune response and the pathogenesis of COVID-19

E Gusev, A Sarapultsev, L Solomatina… - International journal of …, 2022 - mdpi.com
The review aims to consolidate research findings on the molecular mechanisms and
virulence and pathogenicity characteristics of coronavirus disease (COVID-19) causative …

[HTML][HTML] A comprehensive review on the composition, biogenesis, purification, and multifunctional role of exosome as delivery vehicles for cancer therapy

J Li, Y Zhang, PY Dong, GM Yang… - Biomedicine & …, 2023 - Elsevier
All forms of life produce nanosized extracellular vesicles called exosomes, which are
enclosed in lipid bilayer membranes. Exosomes engage in cell-to-cell communication and …

Extracellular vesicles and viruses: two intertwined entities

C Moulin, MJF Crupi, CS Ilkow, JC Bell… - International Journal of …, 2023 - mdpi.com
Viruses share many attributes in common with extracellular vesicles (EVs). The cellular
machinery that is used for EV production, packaging of substrates and secretion is also …

Cardiac tissue model of immune-induced dysfunction reveals the role of free mitochondrial DNA and the therapeutic effects of exosomes

RXZ Lu, N Rafatian, Y Zhao, KT Wagner… - Science …, 2024 - science.org
Despite tremendous progress in the development of mature heart-on-a-chip models, human
cell–based models of myocardial inflammation are lacking. Here, we bioengineered a …

Long-term effects of SARS-CoV-2 in the brain: clinical consequences and molecular mechanisms

AC Granholm - Journal of Clinical Medicine, 2023 - mdpi.com
Numerous investigations have demonstrated significant and long-lasting neurological
manifestations of COVID-19. It has been suggested that as many as four out of five patients …

[HTML][HTML] Toward the next-generation phyto-nanomedicines: Cell-derived nanovesicles (CDNs) for natural product delivery

C Chen, J Wang, M Sun, J Li, HMD Wang - Biomedicine & …, 2022 - Elsevier
Phytochemicals are plant-derived bioactive compounds, which have been widely used for
therapeutic purposes. Due to the poor water-solubility, low bioavailability and non-specific …

Extracellular vesicles as a translational approach for the treatment of COVID-19 disease: an updated overview

E Serretiello, A Ballini, A Smimmo, M Acunzo, M Raimo… - Viruses, 2023 - mdpi.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused a global pandemic
in the years 2020–2022. With a high prevalence, an easy route of transmission, and a long …

Comparison of viral inactivation methods on the characteristics of extracellular vesicles from SARS‐CoV‐2 infected human lung epithelial cells

S Kongsomros, N Pongsakul… - Journal of …, 2022 - Wiley Online Library
The interaction of SARS‐CoV‐2 infection with extracellular vesicles (EVs) is of particular
interest at the moment. Studying SARS‐CoV‐2 contaminated‐EV isolates in instruments …

Intrinsic factors behind long‐COVID: I. Prevalence of the extracellular vesicles

YA El‐Maradny, A Rubio‐Casillas… - Journal of Cellular …, 2023 - Wiley Online Library
It can be argued that the severity of COVID‐19 has decreased in many countries. This could
be a result of the broad coverage of the population by vaccination campaigns, which often …

Adipose stem cells-released extracellular vesicles as a next-generation cargo delivery vehicles: a survey of minimal information implementation, mass production and …

J Chen, R Liu, T Huang, H Sun, H Jiang - Stem Cell Research & Therapy, 2022 - Springer
Objectives To investigate current situation of minimal information implementation highlighted
by minimal information for studies of extracellular vesicles 2018 (MISEV2018) guidelines …