History of cannabis and the endocannabinoid system

MA Crocq - Dialogues in clinical neuroscience, 2020 - Taylor & Francis
This article retraces the story of cannabis from the earliest contacts of humans with the plant
to its subsequent global expansion, its medicinal uses, and the discovery of the …

Cannabis, cannabinoids, and sleep: a review of the literature

KA Babson, J Sottile, D Morabito - Current psychiatry reports, 2017 - Springer
Cannabis, Cannabinoids, and Sleep: a Review of the Literature | Current Psychiatry Reports
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Evolution of the Cannabinoid and Terpene Content during the Growth of Cannabis sativa Plants from Different Chemotypes

O Aizpurua-Olaizola, U Soydaner… - Journal of natural …, 2016 - ACS Publications
The evolution of major cannabinoids and terpenes during the growth of Cannabis sativa
plants was studied. In this work, seven different plants were selected: three each from …

Evolution and Classification of Cannabis sativa (Marijuana, Hemp) in Relation to Human Utilization

E Small - The botanical review, 2015 - Springer
Cannabis sativa has been employed for thousands of years, primarily as a source of a stem
fiber (both the plant and the fiber termed “hemp”) and a resinous intoxicant (the plant and its …

Cannabinoid exposure and altered DNA methylation in rat and human sperm

SK Murphy, N Itchon-Ramos, Z Visco, Z Huang… - Epigenetics, 2018 - Taylor & Francis
Little is known about the reproductive effects of paternal cannabis exposure. We evaluated
associations between cannabis or tetrahydrocannabinol (THC) exposure and altered DNA …

Cultivation of medicinal and aromatic plants for specialty industrial materials

A Lubbe, R Verpoorte - Industrial crops and products, 2011 - Elsevier
Specialty materials such as essential oils, pharmaceuticals, colorants, dyes, cosmetics and
biocides are obtained from plants. Many species of medicinal and aromatic plants (MAPs) …

Pharmacokinetics and pharmacodynamics of cannabinoids

F Grotenhermen - Clinical pharmacokinetics, 2003 - Springer
Abstract Δ 9-Tetrahydrocannabinol (THC) is the main source of the pharmacological effects
caused by the consumption of cannabis, both the marijuana-like action and the medicinal …

Cannabinoid pharmacology: the first 66 years

RG Pertwee - British journal of pharmacology, 2006 - Wiley Online Library
Research into the pharmacology of individual cannabinoids that began in the 1940s, several
decades after the presence of a cannabinoid was first detected in cannabis, is concisely …

Cannabinoid receptors 1 and 2 (CB1 and CB2), their distribution, ligands and functional involvement in nervous system structures—a short review

I Svíženská, P Dubový, A Šulcová - Pharmacology Biochemistry and …, 2008 - Elsevier
In the last 25 years data has grown exponentially dealing with the discovery of the
endocannabinoid system consisting of specific cannabinoid receptors, their endogenous …

Secondary metabolism in cannabis

IJ Flores-Sanchez, R Verpoorte - Phytochemistry reviews, 2008 - Springer
Cannabis sativa L. is an annual dioecious plant from Central Asia. Cannabinoids,
flavonoids, stilbenoids, terpenoids, alkaloids and lignans are some of the secondary …