The renin-angiotensin aldosterone system: pathophysiological role and pharmacologic inhibition

SA Atlas - Journal of managed care pharmacy, 2007 - jmcp.org
BACKGROUND: The renin-angiotensin aldosterone system (RAAS) is a hormonal cascade
that functions in the homeostatic control of arterial pressure, tissue perfusion, and …

Cancer therapy–induced cardiotoxicity: basic mechanisms and potential cardioprotective therapies

VS Hahn, DJ Lenihan, B Ky - Journal of the American Heart …, 2014 - Am Heart Assoc
The patient is a 63-year-old man with a history of wellcontrolled hypertension who is
diagnosed with diffuse large B-cell lymphoma and treated with a doxorubicincontaining …

[HTML][HTML] Cardio-protective and antioxidant properties of caffeic acid and chlorogenic acid: Mechanistic role of angiotensin converting enzyme, cholinesterase and …

OM Agunloye, G Oboh, AO Ademiluyi… - Biomedicine & …, 2019 - Elsevier
Caffeic acid (CAA) and chlorogenic acid (CHA) are important members of hydroxycinnamic
acid with natural antioxidant and cardio-protective properties. The present study aimed to …

[HTML][HTML] Anthracycline-induced cardiotoxicity: A multicenter randomised trial comparing two strategies for guiding prevention with enalapril: The International …

D Cardinale, F Ciceri, R Latini, MG Franzosi… - European journal of …, 2018 - Elsevier
Background Troponin changes over time have been suggested to allow for an early
diagnosis of cardiac injury ensuing cancer chemotherapy; cancer patients with troponin …

Clinical practice guideline for the management of chronic kidney disease in patients infected with HIV: 2014 update by the HIV Medicine Association of the Infectious …

GM Lucas, MJ Ross, PG Stock… - Clinical Infectious …, 2014 - academic.oup.com
It is important to realize that guidelines cannot always account for individual variation among
patients. They are not intended to supplant physician judgment with respect to particular …

Prevention of high-dose chemotherapy–induced cardiotoxicity in high-risk patients by angiotensin-converting enzyme inhibition

D Cardinale, A Colombo, MT Sandri, G Lamantia… - Circulation, 2006 - Am Heart Assoc
Background—An increase in troponin I soon after high-dose chemotherapy (HDC) is a
strong predictor of poor cardiological outcome in cancer patients. This finding has important …

Angiotensin-converting enzyme inhibitory effects by plant phenolic compounds: A study of structure activity relationships

N Al Shukor, J Van Camp, GB Gonzales… - Journal of agricultural …, 2013 - ACS Publications
In this study, 22 phenolic compounds were investigated to inhibit the angiotensin-converting
enzyme (ACE). Tannic acid showed the highest activity (IC50= 230 μM). The IC50 values …

Angiotensin-converting enzyme inhibitors and aortic rupture: a population-based case-control study

DG Hackam, D Thiruchelvam, DA Redelmeier - The Lancet, 2006 - thelancet.com
Background Angiotensin-converting enzyme (ACE) inhibitors prevent the expansion and
rupture of aortic aneurysms in animals. We investigated the association between ACE …

Angiotensin receptor blockers may increase risk of myocardial infarction: unraveling the ARB-MI paradox

MH Strauss, AS Hall - Circulation, 2006 - Am Heart Assoc
838 medication have significant differences with regard to their ancillary pharmacological
properties and thereby also their profile at a molecular/cellular level. Furthermore, these …

[HTML][HTML] Expert opinion on the use of anthracyclines in patients with advanced breast cancer at cardiac risk

PJ Barrett-Lee, JM Dixon, C Farrell, A Jones… - Annals of oncology, 2009 - Elsevier
Anthracyclines are considered to be among the most active agents for the treatment of
breast cancer. However, their use is limited by cumulative, dose-related cardiotoxicity. Such …