Phosphate is freely filtered by the glomerulus and reabsorbed exclusively in the proximal
tubule by two key transporters, NaPiIIA and NaPiIIC, encoded by SLC34A1 and SLC34A3 …

The kidney plays a pivotal role in regulating calcium levels within the body. Approximately
98% of the filtered calcium is reabsorbed in the nephron, and this process is tightly …

Intestinal ischemia-reperfusion (IIR) injury is associated with inflammation and oxidative
stress, yet its precise mechanisms remain not fully understood. IIR injury is closely linked to …

Calcium plays a vital role in various biological processes, including muscle contractions,
blood clotting, skeletal mineralization, and cell signaling. While extracellular calcium makes …

The level of calcium metabolism in urine is closely related to homeostasis, reflecting the
pathological changes of kidneys, bones, and thyroid. It is of great significance to build a …

Pregnancy is associated with elevated demand of most nutrients, with many trace elements
and minerals critical for the development of fetus. In particular, calcium (Ca2+) and …

Introduction Secondary hyperparathyroidism (SHPT) is a common complication of chronic
kidney disease (CKD). It begins as an adaptive increase in parathyroid hormone levels to …

The role of proximal tubules, a major component of the renal tubular structure located at the
renal cortex, in healthy and diseased states has been examined extensively. Along with its …

Aim: The aim of this systematic review is to explore the pathology, diagnosis, treatment, and
genetic basis of Primary Failure of Eruption (PFE) in the field of pediatric dentistry and …

To maintain an optimal body content of phosphorus throughout postnatal life, variable
phosphate absorption from food must be finely matched with urinary excretion. This amazing …