Interleukin-1β secretion induced by mucosa-associated gut commensal bacteria promotes intestinal barrier repair

WJH Wu, M Kim, LC Chang, A Assie… - Gut …, 2022 - Taylor & Francis
The gut microbiota is essential for maintenance and repair of the intestinal epithelial barrier.
As shifts in both intestinal epithelial barrier function and microbiota composition are found in …

Intervention and potential mechanism of non-starch polysaccharides from natural resources on ulcerative colitis: A review

YJ Wang, QM Li, XQ Zha, JP Luo - International Journal of Biological …, 2022 - Elsevier
Ulcerative colitis (UC) is a chronic inflammatory bowel disease of unknown etiology that
affects the colon and rectum. It has evolved into a global burden due to the high incidence in …

Present and future therapeutic approaches to barrier dysfunction

M Fortea, M Albert-Bayo, M Abril-Gil… - Frontiers in …, 2021 - frontiersin.org
There is converging and increasing evidence, but also uncertainty, for the role of abnormal
intestinal epithelial barrier function in the origin and development of a growing number of …

Tributyrin alleviates gut microbiota dysbiosis to repair intestinal damage in antibiotic-treated mice

N Yang, T Lan, Y Han, H Zhao, C Wang, Z Xu, Z Chen… - PLoS …, 2023 - journals.plos.org
Tributyrin (TB) is a butyric acid precursor and has a key role in anti-inflammatory and
intestinal barrier repair effects by slowly releasing butyric acid. However, its roles in gut …

[HTML][HTML] Stachyose modulates gut microbiota and alleviates DSS-induced ulcerative colitis in mice

C Wang, J Bai, B Wang, L Yu, F Tian, J Zhao… - Food Science and …, 2023 - Elsevier
Stachyose is a prebiotic that traditionally extracted from plants, such as vegetable. It has
been demonstrated to alleviate intestinal inflammation by regulating gut microbiota, but the …

Differentiating between tight junction-dependent and tight junction-independent intestinal barrier loss in vivo

SD Chanez-Paredes, S Abtahi, WT Kuo… - … Barrier: Methods and …, 2021 - Springer
The intestinal barrier is an essential component of innate host defense. The single layer of
epithelial cells that line the intestine must balance barrier function with both active …

miR‐10b‐5p rescues leaky gut linked with gastrointestinal dysmotility and diabetes

H Zogg, R Singh, SE Ha, Z Wang, B Jin… - United European …, 2023 - Wiley Online Library
Abstract Background/Aim Diabetes has substantive co‐occurrence with disorders of gut‐
brain interactions (DGBIs). The pathophysiological and molecular mechanisms linking …

Cow milk extracellular vesicle effects on an in vitro model of intestinal inflammation

S Mecocci, A Ottaviani, E Razzuoli, P Fiorani… - Biomedicines, 2022 - mdpi.com
Extracellular vesicles (EVs) are lipid bilayer nano-dimensional spherical structures and act
mainly as signaling mediators between cells, in particular modulating immunity and …

Gut microbiota dysbiosis: The potential mechanisms by which alcohol disrupts gut and brain functions

G Chen, F Shi, W Yin, Y Guo, A Liu, J Shuai… - Frontiers in …, 2022 - frontiersin.org
Alcohol use disorder (AUD) is a high-risk psychiatric disorder and a key cause of death and
disability in individuals. In the development of AUD, there is a connection known as the …

Role of microRNA in inflammatory bowel disease: clinical evidence and the development of preclinical animal models

K Suri, JA Bubier, MV Wiles, LD Shultz, MM Amiji… - Cells, 2021 - mdpi.com
The dysregulation of microRNA (miRNA) is implicated in cancer, inflammation,
cardiovascular disorders, drug resistance, and aging. While most researchers study …