CP‐25 exerts therapeutic effects in mice with dextran sodium sulfate‐induced colitis by inhibiting GRK2 translocation to downregulate the TLR4‐NF‐κB‐NLRP3 …
Y Li, MY Jiang, JY Chen, ZW Xu, JW Zhang, T Li… - IUBMB …, 2021 - Wiley Online Library
Deficiency of G protein‐coupled receptor kinase 2 (GRK2) was found to protect mice from
dextran sulfate sodium (DSS)‐induced colitis. Paeoniflorin‐6′‐O‐benzene sulfonate (CP …
dextran sulfate sodium (DSS)‐induced colitis. Paeoniflorin‐6′‐O‐benzene sulfonate (CP …
[HTML][HTML] Study on drug screening multicellular model for colorectal cancer constructed by three-dimensional bioprinting technology
P Wang, L Sun, C Li, B Jin, H Yang, B Wu… - International Journal of …, 2023 - ncbi.nlm.nih.gov
The existing in vitro models for antitumor drug screening have significant limitations. Many
compounds that inhibit two-dimensional (2D) cultured cells do not exhibit the same …
compounds that inhibit two-dimensional (2D) cultured cells do not exhibit the same …
Paeoniflorin alleviates inflammatory response in IBS-D mouse model via downregulation of the NLRP3 inflammasome pathway with involvement of miR-29a
W Ke, Y Wang, S Huang, S Liu, H Zhu, X Xie, H Yang… - Heliyon, 2022 - cell.com
Paeoniflorin has been traditionally used to treat pain and immunologic derangement in
China. However, its detailed mechanism remains to be illuminated. We investigated the …
China. However, its detailed mechanism remains to be illuminated. We investigated the …
Introduction of colonic and fecal microbiota from an adult pig differently affects the growth, gut health, intestinal microbiota and blood metabolome of newborn piglets
R Qi, Z Zhang, J Wang, X Qiu, Q Wang, F Yang… - Frontiers in …, 2021 - frontiersin.org
Microbiota transplantation is a rapid and effective method for changing and reshaping the
intestinal microbiota and metabolic profile in humans and animals. This study compared the …
intestinal microbiota and metabolic profile in humans and animals. This study compared the …
Development of intestinal injury and restoration of weaned piglets under chronic immune stress
J Yu, C Zheng, J Zheng, G Duan, Q Guo, P Zhang… - Antioxidants, 2022 - mdpi.com
This study aimed to investigate the effects of lipopolysaccharide (LPS)-induced chronic
immune stress on intestinal morphology and function, immune system, oxidative status, and …
immune stress on intestinal morphology and function, immune system, oxidative status, and …
MiRNA-based therapies for the treatment of inflammatory bowel disease: what are we still missing?
Micro-RNAs (miRNAs) are noncoding RNAs usually 24-30 nucleotides long that play a
central role in epigenetic mechanisms of inflammatory diseases and cancers. Recently …
central role in epigenetic mechanisms of inflammatory diseases and cancers. Recently …
肠道微生态与自发性细菌性腹膜炎的关系.
刘玉， 张宇一， 邹颖， 袁伟， 郭红英… - Journal of Clinical …, 2021 - search.ebscohost.com
刘玉,张宇一,邹颖,袁伟,郭红英,梅雪,王介非,钱志平 Page 1 !M"! 肠道微生态与自发性细菌性腹膜炎
的关系 刘玉,张宇一,邹颖,袁伟,郭红英,梅雪,王介非,钱志平 上海市公共卫生临床中心重症肝病科 …
的关系 刘玉,张宇一,邹颖,袁伟,郭红英,梅雪,王介非,钱志平 上海市公共卫生临床中心重症肝病科 …
Intestinal barrier function and performance of broiler chickens fed additional arginine, combination of arginine and glutamine or an amino acid-based solution
R Barekatain, T Chalvon-Demersay, C McLaughlan… - Animals, 2021 - mdpi.com
Simple Summary There is growing evidence that amino acids can influence intestinal barrier
function and inflammation in broiler chickens. Arginine, glutamine, and threonine are …
function and inflammation in broiler chickens. Arginine, glutamine, and threonine are …
Differential response to the course of cryptosporidium parvum infection and its impact on epithelial integrity in differentiated versus undifferentiated human intestinal …
H Lamisere, S Bhalchandra, AV Kane… - Infection and …, 2022 - Am Soc Microbiol
Cryptosporidium is a leading cause of diarrhea and death in young children and untreated
AIDS patients and causes waterborne outbreaks. Pathogenic mechanisms underlying …
AIDS patients and causes waterborne outbreaks. Pathogenic mechanisms underlying …
Distinct transcriptional signatures in purified circulating immune cells drive heterogeneity in disease location in IBD
B Verstockt, S Verstockt, J Cremer… - BMJ Open …, 2023 - bmjopengastro.bmj.com
Objective To infer potential mechanisms driving disease subtypes among patients with
inflammatory bowel disease (IBD), we profiled the transcriptome of purified circulating …
inflammatory bowel disease (IBD), we profiled the transcriptome of purified circulating …