Toll-like receptor 4-related immunostimulatory polysaccharides: Primary structure, activity relationships, and possible interaction models

X Zhang, C Qi, Y Guo, W Zhou, Y Zhang - Carbohydrate polymers, 2016 - Elsevier
Abstract Toll-like receptor (TLR) 4 is an important polysaccharide receptor; however, the
relationships between the structures and biological activities of TLR4 and polysaccharides …

Toll-like receptors from the perspective of cancer treatment

N Javaid, S Choi - Cancers, 2020 - mdpi.com
Toll-like receptors (TLRs) represent a family of pattern recognition receptors that recognize
certain pathogen-associated molecular patterns and damage-associated molecular …

[HTML][HTML] The role of toll-like receptor 4 in tumor microenvironment

J Li, F Yang, F Wei, X Ren - Oncotarget, 2017 - ncbi.nlm.nih.gov
Tumors are closely related to chronic inflammation, during which there are various changes
in inflammatory sites, such as immune cells infiltration, pro-inflammation cytokines …

Lymph nodes and cancer metastasis: new perspectives on the role of intranodal lymphatic sinuses

RC Ji - International journal of molecular sciences, 2016 - mdpi.com
The lymphatic system is essential for transporting interstitial fluid, soluble antigen, and
immune cells from peripheral tissues to lymph nodes (LNs). Functional integrity of LNs is …

Natural polysaccharides and their derivates: A promising natural adjuvant for tumor immunotherapy

Y Li, X Wang, X Ma, C Liu, J Wu, C Sun - Frontiers in Pharmacology, 2021 - frontiersin.org
The treatment process of tumor is advanced with the development of immunotherapy. In
clinical experience, immunotherapy has achieved very significant results. However, the …

Curdlan activates dendritic cells through dectin-1 and toll-like receptor 4 signaling

HS Kim, KH Park, HK Lee, JS Kim, YG Kim… - International …, 2016 - Elsevier
Abstract Curdlan, a β-1, 3-glucan isolated from Alcaligenes faecalis, is an agonist of dectin-1
in various immune cells, including dendritic cells (DCs). However, whether curdlan also …

Migration of dendritic cells to the lymph nodes and its enhancement to drive anti-tumor responses

N Seyfizadeh, R Muthuswamy, DA Mitchell… - Critical reviews in …, 2016 - Elsevier
Better prognoses associated with increased T cell infiltration of tumors, as seen with
chimeric antigen receptor (CAR) T cell therapies and immune checkpoint inhibitors, portray …

Enhancing cancer immunotherapy treatment goals by using nanoparticle delivery system

TA Muluh, Z Chen, Y Li, K Xiong, J Jin… - International Journal of …, 2021 - Taylor & Francis
Recently, there has been an incredible increase in research about the abnormal growth of
cells (neoplasm), focusing on the management, treatment and preventing reoccurrence. It …

The immunoregulatory effects of Chinese herbal medicine on the maturation and function of dendritic cells

J Li, J Li, F Zhang - Journal of ethnopharmacology, 2015 - Elsevier
Abstract Ethnopharmacological relevance Traditional Chinese herbal medicine (CHM) has a
long-history for treatment of various human diseases including tumors, infection …

Regulation of in vivo delivery of nanomedicines by herbal medicines

J Guan, W Chen, M Yang, E Wu, J Qian… - Advanced Drug Delivery …, 2021 - Elsevier
Nanomedicines are of increasing scrutiny due to their improved efficacy and/or mitigated
side effects. They can be integrated with many other therapeutics to further boost the clinical …