PBPK modeling to predict the pharmacokinetics of pantoprazole in different CYP2C19 genotypes
CK Cho, E Ko, JY Mo, P Kang, CG Jang, SY Lee… - Archives of Pharmacal …, 2024 - Springer
Pantoprazole is used to treat gastroesophageal reflux disease (GERD), maintain healing of
erosive esophagitis (EE), and control symptoms related to Zollinger–Ellison syndrome …
erosive esophagitis (EE), and control symptoms related to Zollinger–Ellison syndrome …
[HTML][HTML] Pharmacokinetics and bioequivalence evaluation of omeprazole and sodium bicarbonate dry suspensions in healthy Chinese volunteers
R Zhang, P Guo, J Zhou, P Li, J Wan, C Yang… - Scientific Reports, 2023 - nature.com
Omeprazole and sodium bicarbonate dry suspension are effective treatments for acid-
related disorders. This study compared the bioequivalence and safety of the two …
related disorders. This study compared the bioequivalence and safety of the two …
Prediction of combination effect of quinidine on the pharmacokinetics of tipepidine using a physiologically based pharmacokinetic model
S Hayashi, H Kawaguchi, T Watanabe, I Miyawaki… - Xenobiotica, 2024 - Taylor & Francis
Tipepidine, an antitussive drug, has been reported to have central pharmacological effects
and can be expected to be safely repositioned as treatment for psychiatric disorders. Since …
and can be expected to be safely repositioned as treatment for psychiatric disorders. Since …