Pathogenic human coronavirus infections: causes and consequences of cytokine storm and immunopathology

R Channappanavar, S Perlman - Seminars in immunopathology, 2017 - Springer
Human coronaviruses (hCoVs) can be divided into low pathogenic and highly pathogenic
coronaviruses. The low pathogenic CoVs infect the upper respiratory tract and cause mild …

The cytokine storm of severe influenza and development of immunomodulatory therapy

Q Liu, Y Zhou, Z Yang - Cellular & molecular immunology, 2016 - nature.com
Severe influenza remains unusual in its virulence for humans. Complications or ultimately
death arising from these infections are often associated with hyperinduction of …

Influenza and obesity: its odd relationship and the lessons for COVID-19 pandemic

L Luzi, MG Radaelli - Acta diabetologica, 2020 - Springer
Aims Analyze the relationship between obesity and influenza. Methods Basal hormone
milieu, defective response of both innate and adaptive immune system and sedentariness …

Methylprednisolone or dexamethasone, which one is superior corticosteroid in the treatment of hospitalized COVID-19 patients: a triple-blinded randomized controlled …

K Ranjbar, M Moghadami, A Mirahmadizadeh… - BMC infectious …, 2021 - Springer
Background Although almost a year has passed since the Coronavirus disease 2019
(COVID-19) outbreak and promising reports of vaccines have been presented, we still have …

Clinical remission of a critically ill COVID-19 patient treated by human umbilical cord mesenchymal stem cells: A case report

B Liang, J Chen, T Li, H Wu, W Yang, Y Li, J Li, C Yu… - Medicine, 2020 - journals.lww.com
Interventions: After regular treatment for 12 days, the inflammation symptom of the patient
was still very severe and the potential side effects of corticosteroid were observed. Then …

Medicinal plants and isolated molecules demonstrating immunomodulation activity as potential alternative therapies for viral diseases including COVID-19

HA Alhazmi, A Najmi, SA Javed, S Sultana… - Frontiers in …, 2021 - frontiersin.org
Plants have been extensively studied since ancient times and numerous important chemical
constituents with tremendous therapeutic potential are identified. Attacks of microorganisms …

The acute respiratory distress syndrome

MA Matthay, LB Ware… - The Journal of clinical …, 2012 - Am Soc Clin Investig
The acute respiratory distress syndrome (ARDS) is an important cause of acute respiratory
failure that is often associated with multiple organ failure. Several clinical disorders can …

Controlling cytokine storm is vital in COVID-19

L Tang, Z Yin, Y Hu, H Mei - Frontiers in immunology, 2020 - frontiersin.org
Corona virus disease 2019 (COVID-19) has caused a global outbreak and severely posed
threat to people's health and social stability. Mounting evidence suggests that …

Pathogenesis of influenza-induced acute respiratory distress syndrome

KR Short, EJBV Kroeze, RAM Fouchier… - The Lancet infectious …, 2014 - thelancet.com
Acute respiratory distress syndrome (ARDS) is a fatal complication of influenza infection. In
this Review we provide an integrated model for its pathogenesis. ARDS involves damage to …

Continuing challenges in influenza

RG Webster, EA Govorkova - Annals of the New York Academy …, 2014 - Wiley Online Library
Influenza is an acute respiratory disease in mammals and domestic poultry that emerges
from zoonotic reservoirs in aquatic birds and bats. Although influenza viruses are among the …