[HTML][HTML] Exploring Snake Venoms Beyond the Primary Sequence: from Proteoforms to Protein-Protein Interactions

CR Wang, LO McFarlane, TL Pukala - Toxicon, 2024 - Elsevier
Snakebite envenomation has been a long-standing global issue that is difficult to treat,
largely owing to the flawed nature of current immunoglobulin-based antivenom therapy and …

Streamlining the Analysis of Proteins from Snake Venom

I Oganesyan, TP Jenkins, AH Laustsen… - Journal of Proteome …, 2024 - ACS Publications
Investigating snake venom is necessary for developing new treatments for envenoming and
harnessing the therapeutic potential that lies within venom toxins. Despite considerable …

[HTML][HTML] Comparison of the intrageneric neutralization scope of monospecific, bispecific/monogeneric and polyspecific/monogeneric antisera raised in horses …

A Sánchez, G Durán, Á Segura, M Herrera… - PLOS Neglected …, 2024 - journals.plos.org
Background Snakebite envenomation inflicts a high burden of mortality and morbidity in sub-
Saharan Africa. Antivenoms are the mainstay in the therapy of envenomation, and there is …

A consensus recombinant elapid long-chain α-neurotoxin and how protein folding matters for antibody recognition and neutralization of elapid venoms

V Carpanta, H Clement, I Arenas, G Corzo - Biochemical and Biophysical …, 2024 - Elsevier
Antivenoms are essential in the treatment of the neurotoxicity caused by elapid snakebites.
However, there are elapid neurotoxins, eg, long-chain α-neurotoxins (also known as long …