Hepatocellular Carcinoma in Non-alcoholic Fatty Liver Disease: Emerging Burden

S Batool, K Morton Cuthrell, N Tzenios… - … Research Journal of …, 2022 - publish7promo.com
Liver is the largest solid organ in the body that performs over 100 functions. It removes the
toxins and waste products from the blood stream, maintains healthy blood sugar levels …

Nonalcoholic steatohepatitis-related hepatocellular carcinoma: pathogenesis and treatment

JM Llovet, CE Willoughby, AG Singal… - Nature reviews …, 2023 - nature.com
Nonalcoholic fatty liver disease (NAFLD), including its more severe manifestation,
nonalcoholic steatohepatitis (NASH), has a global prevalence of 20–25% and is a major …

AASLD practice guidance on prevention, diagnosis, and treatment of hepatocellular carcinoma

AG Singal, JM Llovet, M Yarchoan, N Mehta… - Hepatology, 2023 - journals.lww.com
This guidance document provides an updated approach to the prevention, diagnosis, and
treatment of hepatocellular carcinoma (HCC). The prior American Association for the Study …

Global trends in hepatocellular carcinoma epidemiology: implications for screening, prevention and therapy

AG Singal, F Kanwal, JM Llovet - Nature reviews Clinical oncology, 2023 - nature.com
Hepatocellular carcinoma (HCC) mortality rates are increasing globally, and particularly in
the Western world. Cirrhosis remains the predominant risk factor for HCC. However …

Hepatocellular carcinoma surveillance—Utilization, barriers and the impact of changing aetiology

DQ Huang, AG Singal, F Kanwal… - Nature Reviews …, 2023 - nature.com
Hepatocellular carcinoma (HCC) is the third leading cause of cancer death worldwide.
Surveillance for HCC is critical for early detection and treatment, but fewer than one-quarter …

EASL-EASD-EASO Clinical Practice Guidelines on the management of metabolic dysfunction-associated steatotic liver disease (MASLD)

European Association for the Study of the Liver (EASL)… - Obesity Facts, 2024 - karger.com
Metabolic dysfunction-associated steatotic liver disease (MASLD), previously termed non-
alcoholic fatty liver disease (NAFLD), is defined as steatotic liver disease (SLD) in the …

Global burden of liver cancer in males and females: changing etiological basis and the growing contribution of NASH

DJH Tan, VW Setiawan, CH Ng, WH Lim… - Hepatology, 2023 - journals.lww.com
Global burden of liver cancer in males and females: Changing... : Hepatology Global burden of
liver cancer in males and females: Changing etiological basis and the growing contribution of …

Asian perspective on NAFLD-associated HCC

TCF Yip, HW Lee, WK Chan, GLH Wong… - Journal of hepatology, 2022 - Elsevier
Recent data suggest that non-alcoholic fatty liver disease (NAFLD) has become a major
public health problem in Asia, with an updated population prevalence of 34%. In parallel …

NASH and hepatocellular carcinoma: immunology and immunotherapy

M Pinter, DJ Pinato, P Ramadori… - Clinical Cancer Research, 2023 - AACR
The last 10 years have revolutionized our basic understanding of nonalcoholic fatty liver
disease and consequent liver cancer. It has become clear that several innate and adaptive …

Barriers to surveillance for hepatocellular carcinoma in a multicenter cohort

ND Parikh, N Tayob, T Al-Jarrah, J Kramer… - JAMA network …, 2022 - jamanetwork.com
Importance Hepatocellular carcinoma (HCC) surveillance is underused in clinical practice,
which may be owing to patient and clinician barriers. Objective To characterize HCC …