Accelerated epigenetic aging and myopenia in young adult cancer survivors
SC Gehle, D Kleissler, H Heiling, A Deal, Z Xu… - Cancer …, 2023 - Wiley Online Library
Background Young adult cancer survivors experience early aging‐related morbidities and
mortality. Biological aging biomarkers may identify at‐risk survivors and increase our …
mortality. Biological aging biomarkers may identify at‐risk survivors and increase our …
Cross-national and cross-generational evidence that educational attainment may slow the pace of aging in European-descent individuals
Objectives Individuals with more education are at lower risk of developing multiple, different
age-related diseases than their less-educated peers. A reason for this might be that …
age-related diseases than their less-educated peers. A reason for this might be that …
Associations of early-life adversity with later-life epigenetic aging profiles in the multi-ethnic study of atherosclerosis
LL Schmitz, E Duffie, W Zhao, SM Ratliff… - American Journal of …, 2023 - academic.oup.com
Epigenetic biomarkers of accelerated aging have been widely used to predict disease risk
and may enhance our understanding of biological mechanisms between early-life adversity …
and may enhance our understanding of biological mechanisms between early-life adversity …
[HTML][HTML] Sex differences in biological aging and the association with clinical measures in older adults
Females live longer than males, and there are sex disparities in physical health and disease
incidence. However, sex differences in biological aging have not been consistently reported …
incidence. However, sex differences in biological aging have not been consistently reported …
Epigenetic aging and PTSD outcomes in the immediate aftermath of trauma
BackgroundPsychological trauma exposure and posttraumatic stress disorder (PTSD) have
been associated with advanced epigenetic age. However, whether epigenetic aging …
been associated with advanced epigenetic age. However, whether epigenetic aging …
[HTML][HTML] Air pollution and epigenetic aging among Black and White women in the US
Background DNA methylation-based measures of biological aging have been associated
with air pollution and may link pollutant exposures to aging-related health outcomes …
with air pollution and may link pollutant exposures to aging-related health outcomes …
Body size, diet quality, and epigenetic aging: cross-sectional and longitudinal analyses
Epigenetic age is an emerging marker of health that is highly predictive of disease and
mortality risk. There is a lack of evidence on whether lifestyle changes are associated with …
mortality risk. There is a lack of evidence on whether lifestyle changes are associated with …
[HTML][HTML] Metabolic syndrome and epigenetic aging: a twin study
T Föhr, A Hendrix, A Kankaanpää… - International Journal of …, 2024 - nature.com
Abstract Background Metabolic syndrome (MetS) is associated with premature aging, but
whether this association is driven by genetic or lifestyle factors remains unclear. Methods …
whether this association is driven by genetic or lifestyle factors remains unclear. Methods …
A DNA methylation based measure outperforms circulating CRP as a marker of chronic inflammation and partly reflects the monocytic response to long‐term …
A key hallmark in the age‐related dysfunction of physiological systems is disruption related
to the regulation of inflammation, often resulting in a chronic, low‐grade inflammatory state …
to the regulation of inflammation, often resulting in a chronic, low‐grade inflammatory state …
[HTML][HTML] Host fecal DNA specific methylation signatures mark gut dysbiosis and inflammation in children affected by autism spectrum disorder
M Cuomo, L Coretti, D Costabile, R Della Monica… - Scientific Reports, 2023 - nature.com
The gut-brain axis involves several bidirectional pathway communications including
microbiome, bacterial metabolites, neurotransmitters as well as immune system and is …
microbiome, bacterial metabolites, neurotransmitters as well as immune system and is …