[HTML][HTML] Aptamers—diagnostic and therapeutic solution in SARS-CoV-2
T Wandtke, E Wędrowska, M Szczur… - International journal of …, 2022 - mdpi.com
The SARS-CoV-2 virus is currently the most serious challenge to global public health. Its
emergence has severely disrupted the functioning of health services and the economic and …
emergence has severely disrupted the functioning of health services and the economic and …
Overview of targets and potential drugs of SARS-CoV-2 according to the viral replication
Y Zhang, LV Tang - Journal of proteome research, 2020 - ACS Publications
Since the novel coronavirus pandemic, people around the world have been touched in
varying degrees, and this pandemic has raised a major global health concern. As there is no …
varying degrees, and this pandemic has raised a major global health concern. As there is no …
Repositioning PARP inhibitors for SARS‐CoV‐2 infection (COVID‐19); a new multi‐pronged therapy for acute respiratory distress syndrome?
Clinically approved PARP inhibitors (PARPi) have a mild adverse effect profile and are well
tolerated as continuous daily oral therapy. We review the evidence that justifies the …
tolerated as continuous daily oral therapy. We review the evidence that justifies the …
Virtual screening and dynamics of potential inhibitors targeting RNA binding domain of nucleocapsid phosphoprotein from SARS-CoV-2
The emergence of the coronavirus disease-2019 pandemic has led to an outbreak in the
world. The SARS-CoV-2 is seventh and latest in coronavirus family with unique …
world. The SARS-CoV-2 is seventh and latest in coronavirus family with unique …
Computational guided identification of novel potent inhibitors of N-terminal domain of nucleocapsid protein of severe acute respiratory syndrome coronavirus 2
Abstract The Coronavirus Disease 2019, caused by the severe acute respiratory syndrome
coronavirus 2 is an exceptionally contagious disease that leads to global epidemics with …
coronavirus 2 is an exceptionally contagious disease that leads to global epidemics with …
Targeting SARS-CoV-2 nucleocapsid oligomerization: Insights from molecular docking and molecular dynamics simulations
The outbreak of COVID-19 caused by SARS-CoV-2 virus continually led to infect a large
population worldwide. Currently, there is no specific viral protein-targeted therapeutics. The …
population worldwide. Currently, there is no specific viral protein-targeted therapeutics. The …
Understanding the phase separation characteristics of nucleocapsid protein provides a new therapeutic opportunity against SARS-CoV-2
To date, tens of millions of people have been infected with severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), causing the outbreak of the respiratory disease …
syndrome coronavirus 2 (SARS-CoV-2), causing the outbreak of the respiratory disease …
[HTML][HTML] An overview of the crystallized structures of the SARS-CoV-2
MI Ionescu - The protein journal, 2020 - Springer
Many research teams all over the world focus their research on the SARS-CoV-2, the new
coronavirus that causes the so-called COVID-19 disease. Most of the studies identify the …
coronavirus that causes the so-called COVID-19 disease. Most of the studies identify the …
The impact of structural bioinformatics tools and resources on SARS-CoV-2 research and therapeutic strategies
SARS-CoV-2 is the causative agent of COVID-19, the ongoing global pandemic. It has
posed a worldwide challenge to human health as no effective treatment is currently …
posed a worldwide challenge to human health as no effective treatment is currently …
[HTML][HTML] Zinc and copper ions differentially regulate prion-like phase separation dynamics of pan-virus nucleocapsid biomolecular condensates
A Monette, AJ Mouland - Viruses, 2020 - mdpi.com
Liquid-liquid phase separation (LLPS) is a rapidly growing research focus due to numerous
demonstrations that many cellular proteins phase-separate to form biomolecular …
demonstrations that many cellular proteins phase-separate to form biomolecular …