Proteomics revealed composition-and size-related regulators for hepatic impairments induced by silica nanoparticles

X Zhao, R Ma, A Abulikemu, Y Qi, X Liu, J Wang… - Science of The Total …, 2024 - Elsevier
Along with the growing production and application of silica nanoparticles (SiNPs), increased
human exposure and ensuing safety evaluation have progressively attracted concern …

Proteomic analysis of frozen–thawed spermatozoa with different levels of freezability in dairy goats

P Sun, G Zhang, M Xian, G Zhang, F Wen… - International Journal of …, 2023 - mdpi.com
The results of artificial insemination (AI) are adversely affected by changes in sperm motility
and function throughout the cryopreservation procedure. The proteome alterations of frozen …

Study on the mechanism of arsenic-induced renal injury based on SWATH proteomics technology

X Chen, X Yan, X Tang, Y Wang, X Zhang… - Journal of Trace …, 2024 - Elsevier
Abstract Background Arsenic (As) poisoning is a worldwide endemic disease affecting
thousands of people. As is excreted mainly through the renal system, and arsenic has toxic …

Application of cinnamaldehyde solid lipid nanoparticles in strawberry preservation

S Li, J Chen, Y Liu, Q Zheng, W Tan, X Feng, K Feng… - Horticulturae, 2023 - mdpi.com
Strawberries are a popular food. However, the growth and reproduction of microorganisms
on the surface of strawberries change their quality and may cause food poisoning. We …

Investigating the fate and toxicity of green synthesized gold nanoparticles in albino mice

N Akkam, AAA Aljabali, Y Akkam… - Drug Development …, 2023 - Taylor & Francis
Objective This study aims to investigate the acute and chronic adverse effects of∼ 50 nm
(nanometer) gold nanoparticles (AuNPs) synthesized using Ziziphus zizyphus leaf extract in …

l-Cysteine-Triggered Regulation of the Mitochondrial Energy Metabolism To Enhance Chemotherapy of Triple-Negative Breast Cancer

H Ge, J Du, J Zheng, N Xu, Q Yao, S Long… - ACS Materials …, 2024 - ACS Publications
Although cisplatin has widely been used for treating triple-negative breast cancer (TNBC), its
anticancer effect remains unsatisfactory, due to the heavy resistance. In this study, oxidative …

Effect of the ROCK inhibitor fasudil on the brain proteomic profile in the tau transgenic mouse model of Alzheimer's disease

R Collu, Z Yin, E Giunti, S Daley, M Chen… - Frontiers in Aging …, 2024 - frontiersin.org
Introduction The goal of this study is to explore the pharmacological potential of the amyloid-
reducing vasodilator fasudil, a selective Ras homolog (Rho)-associated kinases (ROCK) …

[HTML][HTML] iIMPACT: integrating image and molecular profiles for spatial transcriptomics analysis

X Jiang, S Wang, L Guo, B Zhu… - Genome …, 2024 - genomebiology.biomedcentral.com
Current clustering analysis of spatial transcriptomics data primarily relies on molecular
information and fails to fully exploit the morphological features present in histology images …

Superresolved spatial transcriptomics transferred from a histological context

S Wang, X Zhou, Y Kong, H Lu - Applied Intelligence, 2023 - Springer
Spatially resolved transcriptomics (SRT) is a vital technique in biology that allows for gene
expression measurement at the resolution of individual spots while preserving spatial …

Integrating image and molecular profiles for spatial transcriptomics analysis

X Jiang, S Wang, L Guo, Z Wen, L Jia, L Xu, G Xiao… - bioRxiv, 2023 - biorxiv.org
The spatially resolved transcriptomics (SRT) field has revolutionized our ability to
comprehensively leverage image and molecular profiles to elucidate spatial organization of …