Role of galectin 3 binding protein in cancer progression: a potential novel therapeutic target
E Capone, S Iacobelli, G Sala - Journal of translational medicine, 2021 - Springer
The lectin galactoside-binding soluble 3 binding protein (LGALS3BP) is a secreted,
hyperglycosylated protein expressed by the majority of human cells. It was first identified as …
hyperglycosylated protein expressed by the majority of human cells. It was first identified as …
Western diet contributes to the pathogenesis of non-alcoholic steatohepatitis in male mice via remodeling gut microbiota and increasing production of 2-oleoylglycerol
The interplay between western diet and gut microbiota drives the development of non-
alcoholic fatty liver disease and its progression to non-alcoholic steatohepatitis. However …
alcoholic fatty liver disease and its progression to non-alcoholic steatohepatitis. However …
Mechanism of regulating macrophages/osteoclasts in attenuating wear particle-induced aseptic osteolysis
Z Yin, G Gong, X Liu, J Yin - Frontiers in Immunology, 2023 - frontiersin.org
Joint replacement surgery is the most effective treatment for end-stage arthritis. Aseptic
loosening caused by periprosthetic osteolysis is a common complication after joint …
loosening caused by periprosthetic osteolysis is a common complication after joint …
Extracellular vesicles from human iPSC-derived neural stem cells: miRNA and protein signatures, and anti-inflammatory and neurogenic properties
Grafting of neural stem cells (NSCs) derived from human induced pluripotent stem cells
(hiPSCs) has shown promise for brain repair after injury or disease, but safety issues have …
(hiPSCs) has shown promise for brain repair after injury or disease, but safety issues have …
Epigenome-wide association study of incident type 2 diabetes: a meta-analysis of five prospective European cohorts
E Fraszczyk, AMW Spijkerman, Y Zhang, S Brandmaier… - Diabetologia, 2022 - Springer
Aims/hypothesis Type 2 diabetes is a complex metabolic disease with increasing
prevalence worldwide. Improving the prediction of incident type 2 diabetes using epigenetic …
prevalence worldwide. Improving the prediction of incident type 2 diabetes using epigenetic …
Regulation of mitogen-activated protein kinase signaling pathways by the ubiquitin-proteasome system and its pharmacological potential
S Mathien, C Tesnière, S Meloche - Pharmacological Reviews, 2021 - ASPET
Mitogen-activated protein kinase (MAPK) cascades are evolutionarily conserved signaling
pathways that play essential roles in transducing extracellular environmental signals into …
pathways that play essential roles in transducing extracellular environmental signals into …
Zebrafish Galectin 3 binding protein is the target antigen of the microglial 4C4 monoclonal antibody
M Rovira, M Miserocchi, A Montanari… - Developmental …, 2023 - Wiley Online Library
Background Two decades ago, the fish‐specific monoclonal antibody 4C4 was found to be
highly reactive to zebrafish microglia, the macrophages of the central nervous system. This …
highly reactive to zebrafish microglia, the macrophages of the central nervous system. This …
Genome-wide aggregated trans-effects on risk of type 1 diabetes: a test of the “omnigenic” sparse effector hypothesis of complex trait genetics
A Iakovliev, SJ McGurnaghan, C Hayward… - The American Journal of …, 2023 - cell.com
The" omnigenic" hypothesis postulates that the polygenic effects of common SNPs on a
typical complex trait are mediated through trans-effects on expression of a relatively sparse …
typical complex trait are mediated through trans-effects on expression of a relatively sparse …
Circular RNA circARHGEF28 inhibited the progression of prostate cancer via the miR‐671‐5p/LGALS3BP/NF‐κB axis
K Guo, J Shi, Z Tang, C Lai, C Liu, K Li, Z Li… - Cancer …, 2023 - Wiley Online Library
Circular RNAs (circRNAs) play crucial roles in various biological processes, including
prostate cancer (PCa). However, the precise roles and mechanism of circRNAs are …
prostate cancer (PCa). However, the precise roles and mechanism of circRNAs are …
Long noncoding RNA TARL promotes antibacterial activity and prevents bacterial escape in Miichthys miiuy through suppression of TAK1 downregulation
W Zheng, X Lv, S Xin, Y Sun, T Xu - Science China Life Sciences, 2023 - Springer
Noncoding RNA (ncRNA) is an important regulatory factor that plays a major role in innate
immunity. However, most studies on ncRNA have focused on mammals, resulting in a …
immunity. However, most studies on ncRNA have focused on mammals, resulting in a …