A pandemic is a global epidemic. Infectious diseases have killed more humans than others
in history. The history of global pandemic diseases has shaped human history and has …

Influenza virus remains a serious public health burden due to ongoing viral evolution.
Vaccination remains the best measure of prophylaxis, yet current seasonal vaccines elicit …

Ageing is often associated with a reduction in antibody-secreting cell formation and vaccine-
induced antibody titres, resulting in poor vaccine responses among the older population …

Targeting conserved influenza virus epitopes could improve cross-reactive immunity and
alleviate the burden of annual vaccine component reformulation. Here, free influenza stalk …

Las vacunas antigripales actuales solo contienen como inmunógeno a la hemaglutinina
(HA) gripal completa determinando una inmunidad poco duradera. Este fenómeno se debe …

Despite the availability of seasonal vaccines and antiviral medications, influenza virus
continues to be a major health concern and pandemic threat due to the continually changing …

Os vírus influenza ocasionam 290 a 650 mil mortes mundialmente durante suas epidemias
anuais, sendo assim de especial relevância para a saúde pública. A sua alta taxa de …

Viral entry proteins facilitate viral entry into host cells through receptor binding and
membrane fusion. They play a critical role in the viral life cycle and, as prominent surface …

The Orthomyxoviridae family of the Monengivirales order contains in uenza A viruses. They
have eight negative-sense RNA segments that code for 12 proteins, including the surface …

In the past decade, the discovery and characterization of broadly neutralizing antibodies
(bnAbs) to the highly conserved stem region of influenza hemagglutinin (HA) have provided …