Abstract Purpose of Review Elevated plasma levels of low-density lipoprotein cholesterol
(LDL-C) are a major risk factor for atherosclerotic cardiovascular disease (ASCVD), and …

The metabolism in eukaryotic cells is a highly ordered system involving various cellular
compartments, which fluctuates based on physiological rhythms. Organelles, as the smallest …

Simple Summary The main challenge in high-grade serous carcinoma management is to
unveil therapeutic approaches to overcome chemoresistance. Drug combinations and …

Hyperlipidemia is a risk factor for the development of fatty liver and cardiovascular diseases
such as atherosclerosis and coronary heart disease, and hence, cholesterol-lowering drugs …

Introduction: Colorectal cancer is one of the most prevalent life-threatening malignant tumors
with high incidence and mortality. However, the efficacy of current therapeutic regimens is …

Foxtail millet proteins and their hydrolysates have the potential to prevent atherosclerosis
(AS). In our present study, a novel Bowman-Birk type major trypsin inhibitor from foxtail millet …

The field of antisense oligonucleotide (ASO)-based therapies have been making strides in
precision medicine due to their potent therapeutic application. Early successes in treating …

Hepatosteatosis is characterized by abnormal accumulation of triglycerides (TG), leading to
prolonged and chronic inflammatory infiltration. To date, there is still a lack of effective and …

Adenosine triphosphate binding cassette (ABC) transporters are a broad family of
membrane protein complexes that use energy to transport molecules across cells and/or …

Background Pharmacomicrobiomics, which has recently emerged as a new strategy for
personalized medicine, is the investigation of the influence of microbial variability on drug …