Environmental Sensing and Signal Transduction Pathways Regulating Morphopathogenic Determinants of Candida albicans

S Biswas, P Van Dijck, A Datta - Microbiology and molecular …, 2007 - Am Soc Microbiol
Candida albicans is an opportunistic fungal pathogen that is found in the normal
gastrointestinal flora of most healthy humans. However, under certain environmental …

The metabolic basis of Candida albicans morphogenesis and quorum sensing

TL Han, RD Cannon, SG Villas-Bôas - Fungal Genetics and Biology, 2011 - Elsevier
Candida albicans is a polymorphic fungus that has the ability to rapidly switch between
yeast and filamentous forms. The morphological transition appears to be a critical virulence …

Metabolism in fungal pathogenesis

IV Ene, S Brunke, AJP Brown… - Cold Spring …, 2014 - perspectivesinmedicine.cshlp.org
Fungal pathogens must assimilate local nutrients to establish an infection in their
mammalian host. We focus on carbon, nitrogen, and micronutrient assimilation mechanisms …

Adaptations of Candida albicans for growth in the mammalian intestinal tract

A Rosenbach, D Dignard, JV Pierce, M Whiteway… - Eukaryotic …, 2010 - Am Soc Microbiol
Although the fungus Candida albicans is a commensal colonizer of humans, the organism is
also an important opportunistic pathogen. Most infections caused by C. albicans arise from …

Property Differences among the Four Major Candida albicans Strain Clades

DM MacCallum, L Castillo, K Nather, CA Munro… - Eukaryotic …, 2009 - Am Soc Microbiol
ABSTRACT A selection of 43 Candida albicans isolates, chosen to represent the four major
strain clades of the species and also intraclade diversity, was screened for their virulence in …

Effect of growth media, pH and temperature on yeast to hyphal transition in Candida albicans

SG Nadeem, A Shafiq, ST Hakim, Y Anjum, SU Kazm - 2013 - philpapers.org
The transition of C. albicans from unicellular yeast form to filamentous form ie,
pseudohyphae and hyphae is referred to as morphogenesis. C. albicans has the ability to …

Candida species Rewired Hyphae Developmental Programs for Chlamydospore Formation

B Böttcher, C Pöllath, P Staib, B Hube… - Frontiers in …, 2016 - frontiersin.org
Chlamydospore formation is a characteristic of many fungal species, among them the
closely related human-pathogenic dimorphic yeasts Candida albicans and C. dubliniensis …

Impact of the unfolded protein response upon genome-wide expression patterns, and the role of Hac1 in the polarized growth, of Candida albicans

TT Wimalasena, B Enjalbert, T Guillemette… - Fungal genetics and …, 2008 - Elsevier
The unfolded protein response (UPR) regulates the expression of genes involved in the
protein secretory pathway and in endoplasmic reticulum (ER) stress in yeasts and …

[HTML][HTML] Genome-wide analysis of Candida albicans gene expression patterns during infection of the mammalian kidney

LA Walker, DM MacCallum, G Bertram… - Fungal Genetics and …, 2009 - Elsevier
Global analysis of the molecular responses of microbial pathogens to their mammalian hosts
represents a major challenge. To date few microarray studies have been performed on …

Aneuploid Chromosomes Are Highly Unstable during DNA Transformation of Candida albicans

K Bouchonville, A Forche, KES Tang, A Selmecki… - Eukaryotic …, 2009 - Am Soc Microbiol
Candida albicans strains tolerate aneuploidy, historically detected as karyotype alterations
by pulsed-field gel electrophoresis and more recently revealed by array comparative …