Nucleoside-Modified mRNA Vaccines Protect IFNAR–/– Mice against Crimean-Congo Hemorrhagic Fever Virus Infection

S Appelberg, L John, N Pardi, Á Végvári… - Journal of …, 2022 - Am Soc Microbiol
Crimean-Congo hemorrhagic fever (CCHF), caused by Crimean-Congo hemorrhagic fever
virus (CCHFV), is on the World Health Organizations' list of prioritized diseases and …

Vaccination against bacterial infections: challenges, progress, and new approaches with a focus on intracellular bacteria

A Osterloh - Vaccines, 2022 - mdpi.com
Many bacterial infections are major health problems worldwide, and treatment of many of
these infectious diseases is becoming increasingly difficult due to the development of …

Demystifying mRNA vaccines: an emerging platform at the forefront of cryptic diseases

NZ Rouf, S Biswas, N Tarannum, LM Oishee… - RNA biology, 2022 - Taylor & Francis
Messenger RNA (mRNA) vaccines have been studied for decades, but only recently, during
the COVID-19 pandemic, has the technology garnered noteworthy attention. In contrast to …

Contributions of the international plant science community to the fight against infectious diseases in humans—part 2: Affordable drugs in edible plants for endemic and …

W He, C Baysal, M Lobato Gomez… - Plant biotechnology …, 2021 - Wiley Online Library
The fight against infectious diseases often focuses on epidemics and pandemics, which
demand urgent resources and command attention from the health authorities and media …

A Pvs25 mRNA vaccine induces complete and durable transmission-blocking immunity to Plasmodium vivax

N Kunkeaw, W Nguitragool, E Takashima… - npj Vaccines, 2023 - nature.com
Plasmodium vivax (P. vivax) is the major malaria parasite outside of Africa and no vaccine is
available against it. A vaccine that interrupts parasite transmission (transmission-blocking …

Extracellular vesicles in malaria: an agglomeration of two decades of research

T Opadokun, P Rohrbach - Malaria Journal, 2021 - Springer
Malaria is a complex parasitic disease, caused by Plasmodium spp. More than a century
after the discovery of malaria parasites, this disease continues to pose a global public health …

Vaccines and monoclonal antibodies: new tools for malaria control

K Miura, Y Flores-Garcia, CA Long… - Clinical Microbiology …, 2024 - Am Soc Microbiol
Malaria remains one of the biggest health problems in the world. While significant reductions
in malaria morbidity and mortality had been achieved from 2000 to 2015, the favorable trend …

mRNA-based therapeutics: looking beyond COVID-19 vaccines

H Parhiz, EN Atochina-Vasserman, D Weissman - The Lancet, 2024 - thelancet.com
Recent advances in mRNA technology and its delivery have enabled mRNA-based
therapeutics to enter a new era in medicine. The rapid, potent, and transient nature of mRNA …

Rapid response to pandemic threats: immunogenic epitope detection of pandemic pathogens for diagnostics and vaccine development using peptide microarrays

K Heiss, J Heidepriem, N Fischer… - Journal of proteome …, 2020 - ACS Publications
Emergence and re-emergence of pathogens bearing the risk of becoming a pandemic threat
are on the rise. Increased travel and trade, growing population density, changes in …

The potential of nanomedicine to unlock the limitless applications of mRNA

L Taina-González, M de la Fuente - Pharmaceutics, 2022 - mdpi.com
The year 2020 was a turning point in the way society perceives science. Messenger RNA
(mRNA) technology finally showed and shared its potential, starting a new era in medicine …