Early life stress and development: potential mechanisms for adverse outcomes
Background Chronic and/or extreme stress in early life, often referred to as early adversity,
childhood trauma, or early life stress, has been associated with a wide range of adverse …
childhood trauma, or early life stress, has been associated with a wide range of adverse …
[HTML][HTML] More than a feeling: A unified view of stress measurement for population science
Stress can influence health throughout the lifespan, yet there is little agreement about what
types and aspects of stress matter most for human health and disease. This is in part …
types and aspects of stress matter most for human health and disease. This is in part …
[图书][B] Ecology of the brain: The phenomenology and biology of the embodied mind
T Fuchs - 2017 - books.google.com
Present day neuroscience places the brain at the centre of study. But what if researchers
viewed the brain not as the foundation of life, rather as a mediating organ? Ecology of the …
viewed the brain not as the foundation of life, rather as a mediating organ? Ecology of the …
Early stress-induced impaired microglial pruning of excitatory synapses on immature CRH-expressing neurons provokes aberrant adult stress responses
Several mental illnesses, characterized by aberrant stress reactivity, often arise after early-
life adversity (ELA). However, it is unclear how ELA affects stress-related brain circuit …
life adversity (ELA). However, it is unclear how ELA affects stress-related brain circuit …
Biological embedding of childhood adversity: from physiological mechanisms to clinical implications
Background Adverse psychosocial exposures in early life, namely experiences such as child
maltreatment, caregiver stress or depression, and domestic or community violence, have …
maltreatment, caregiver stress or depression, and domestic or community violence, have …
Biological aging in childhood and adolescence following experiences of threat and deprivation: A systematic review and meta-analysis.
Life history theory argues that exposure to early life adversity (ELA) accelerates
development, although existing evidence for this varies. We present a meta-analysis and …
development, although existing evidence for this varies. We present a meta-analysis and …
The future of rodent models in depression research
Currently, over 300 million people worldwide have depression, and the socioeconomic
burden of this debilitating disorder is anticipated to increase markedly over the coming …
burden of this debilitating disorder is anticipated to increase markedly over the coming …
Annual research review: Early adversity, the hypothalamic–pituitary–adrenocortical axis, and child psychopathology
Background Research on early adversity, stress biology, and child development has grown
exponentially in recent years. Findings We review the current evidence for the hypothalamic …
exponentially in recent years. Findings We review the current evidence for the hypothalamic …
Future directions in childhood adversity and youth psychopathology
KA McLaughlin - Future work in clinical child and adolescent …, 2018 - taylorfrancis.com
Despite long-standing interest in the influence of adverse early experiences on mental
health, systematic scientific inquiry into childhood adversity and developmental outcomes …
health, systematic scientific inquiry into childhood adversity and developmental outcomes …
Sex differences and stress across the lifespan
TL Bale, CN Epperson - Nature neuroscience, 2015 - nature.com
Sex differences in stress responses can be found at all stages of life and are related to both
the organizational and activational effects of gonadal hormones and to genes on the sex …
the organizational and activational effects of gonadal hormones and to genes on the sex …