The gonadal steroids, including androgens, estrogens and progestogens, are involved in
the control of body fat distribution in humans. Nevertheless, not only the size and localization …

Neurodegenerative diseases, including Alzheimer disease (AD), Parkinson disease (PD),
multiple sclerosis (MS), amyotrophic lateral sclerosis (ALS), and Huntington disease, are …

Background: The etiology of benign prostatic hyperplasia and prostate cancer are unknown,
with ageing being the greatness risk factor. Methods: This new perspective evaluates the …

Sex differences in morbidity and mortality have been reported in the cystic fibrosis (CF)
population worldwide. However, it is unclear why CF women have worse clinical outcomes …

Since it was first synthesized in 1935, testosterone (T) has been viewed as the mythical
Fountain of Youth, promising rejuvenation, restoring sexual appetites, growing stronger …

In this current review, research spanning the last decade (such as transcriptomic studies,
phenotypic observations, and confirmed comorbidities) has been synthesized into an …

In the past two decades, oxidative stress (OS) has drawn a lot of interest due to the
revelation that individuals with many persistent disorders including diabetes, polycystic …

Simple Summary Immune-mediated inflammatory diseases (IMIDs) are growing in
prevalence and relevance in our society, entailing notable consequences for the individual …

The importance of sex differences is increasingly acknowledged in the incidence and
treatment of disease. Accumulating clinical evidence demonstrates that sex differences are …

Genomic instability can trigger cellular responses that include checkpoint activation,
senescence and inflammation,. Although genomic instability has been extensively studied in …