• The specific situation of the patient. Unless otherwise provided for by national regulations,
off-label use of medication should be limited to situations where it is in the patient's interest …

Hypertension is the most frequent chronic and non-communicable disease all over the
world, with about 1.5 billion affected individuals worldwide. Its impact is currently growing …

We examined whether renal denervation (RDN) reduced blood pressure (BP), improved
glomerular filtration rate, albuminuria, and left ventricular mass in sheep with hypertensive …

Despite availability of effective drugs for hypertension therapy, significant numbers of
hypertensive patients fail to achieve recommended blood pressure levels on≥ 3 …

Hypertension is a major health concern globally. Elevated blood pressure, initiated and
maintained by the brain, is defined as neurogenic hypertension (NH), which accounts for …

Objectives The authors performed a systematic review and meta-analysis to determine the
efficacy of renal denervation (RDN) in patients with refractory ventricular arrhythmias (VA) or …

The kidney is innervated by afferent sensory and efferent sympathetic nerve fibers.
Norepinephrine (NE) is the primary neurotransmitter for post-ganglionic sympathetic …

In the general population, the prevalence of moderate and severe chronic kidney disease
(CKD) is usually below 5% but this figure is often higher in specific groups of patients such …

Renalase is a~ 38 kDa flavin-adenine dinucleotide (FAD) domain-containing protein that
can function as a cytokine and an anomerase. It is emerging as a novel regulator of …

The global burden of chronic kidney disease is rising. The etiologies, heterogeneous, and
arterial hypertension, are key factors contributing to the development and progression of …