Screening assays and methods

JC Love, HL Ploegh, J Ronan - US Patent 9,463,431, 2016 - Google Patents
US9463431B2 - Screening assays and methods - Google Patents US9463431B2 -
Screening assays and methods - Google Patents Screening assays and methods …

The induction of resting B cell differentiation does not require T cell contact

M Julius, L Haughn - European journal of immunology, 1992 - Wiley Online Library
AT cell clone as well as immediately ex vivo CD4+ lymph node T cells are shown to support
the differentiation of co‐cultured resting B cells in the absence of T cell‐B cell contact …

Relative frequencies of secondary B cells activated by cognate vs. other mechanisms

JG Johnson, R Jemmerson - European journal of immunology, 1991 - Wiley Online Library
Three distinct mechanisms for the activation of secondary B cells to antibody‐forming cells
have been examined in splenic fragment cultures. The clonal response to a protein antigen …

Interleukin-5

T Honjo, K Takatsu - Peptide Growth Factors and Their Receptors I, 1990 - Springer
The immune response to a foreign antigen is regulated by a series of interactions between T
lymphocytes (T cells), B lymphocytes (B cells), and macrophages. During this process B …

T helper cell-b cell interaction: the roles of direct Th-B cell contact and cell-free mediators.

RJ Hodes - Seminars in Immunology, 1989 - europepmc.org
The antibody responses of B cells to most protein antigens are dependent upon signals
provided by T helper cells; the nature of the signals which mediate the interactions of these …

Induction of interleukin-5 responsiveness in resting B cells by engagement of the antigen receptor and perception of a second polyclonal activation signal

GD Wetzel - Cellular immunology, 1991 - Elsevier
Experiments were performed to examine the nature of agents which could induce IL-5
responsiveness in small, resting splenic B lymphocytes. First, IL-5 increased plaque forming …

Interleukin-5

CC Kok, GT Schwenger, RIW Osmond… - The cytokine …, 2003 - books.google.com
Interleukin-5 (IL-5) is produced by T lymphocytes as a glycoprotein with an Mr of 40–45 kDa
and is unusual among the T-cell-produced cytokines in being a disulphide-linked …

Collaboration between T and B cells

V Sanders, ES Vitetta - Cytokines and B lymphocytes, 1990 - books.google.com
Cellular collaboration is an important feature of the immune system and it involves the
recognition of cell surface-associated molecules on one cell by specific receptors on …

Role of lymphokines in the immune system

ES Vitetta, WE Paul - Peptide Growth Factors and Their Receptors II, 1990 - Springer
The immune system has evolued to recognize and respond to foreign substances that are
often associated with pathogenic agents. This response, if successful, leads to the …

细胞性和体液性排斥反应的不同机制与内在联系(续)

石炳毅, 许晓光 - 中华器官移植杂志, 2008 - cqvip.com
2. T, B 淋巴细胞的相互作用(第二信号): 经抗原刺激的初始T 淋巴细胞被抗原提呈细胞(APC)“
捕捉” 后被特异性激活, 活化的T 淋巴细胞表面表达CD40 配体(CD40L), 并分泌细胞因子. 随后 …