The centenary of insulin discovery represents an important opportunity to transform diabetes
from a fatal diagnosis into a medically manageable chronic condition. Insulin is a key …

Mesenchymal stem cells (MSCs) can be widely isolated from various tissues including bone
marrow, umbilical cord, and adipose tissue, with the potential for self-renewal and …

In East Central Europe (ECE), democracy and the rule of law are under siege, most notably
in Hungary and Poland and, to a lesser extent, also in the Czech Republic and Slovakia …

The increasing global prevalence of type 2 diabetes mellitus (T2DM) and chronic kidney
disease (CKD) has prompted research efforts to tackle the growing epidemic of diabetic …

Background Obesity increases the risk of several chronic diseases, but the extent to which
the obesity-related loss of disease-free years varies by lifestyle category and across …

Evidence concerning coronavirus disease-19 (covid-19) in pregnancy is still scarce and
scattered. This meta-analysis aims to evaluate maternal and neonatal outcomes in covid-19 …

Understanding nephron loss is a primary strategy for preventing CKD progression. Death of
renal tubular cells may occur by apoptosis during developmental and regenerative …

Mitochondria are essential organelles in physiology and kidney diseases, because they
produce cellular energy required to perform their function. During mitochondrial metabolism …

Kidney disease represents a serious global health problem. One of the main concerns is its
late diagnosis, only feasible in a progressed disease state. The lack of a clinical …

Persistent low-grade inflammation and premature ageing are hallmarks of the uremic
phenotype and contribute to impaired health status, reduced quality of life, and premature …