Purpose Polygenic risk influences susceptibility to cancer. We assessed whether polygenic
risk scores could be used in conjunction with other predictors of future disease status in cost …

Background: Evidence for a potential link between air pollution and rheumatoid arthritis (RA)
is inconsistent, and the modified effect of genetic susceptibility on the relationship between …

Researchers aim to develop polygenic risk scores as a tool to prevent and more effectively
treat serious diseases, disorders and conditions such as breast cancer, type 2 diabetes …

The 2010 special issue of Journal of Health and Social Behavior, titled “Fifty Years of
Medical Sociology,” defined the contours of the medical sociological perspective. We use …

Improvement in risk prediction of atherosclerotic cardiovascular disease (ASCVD) using
information on the genetic predisposition at an individual level might offer new possibilities …

Inflammatory bowel disease (IBD), with Crohn's disease and ulcerative colitis as main
subtypes, is a prototypical multifactorial disease with both genetic and environmental factors …

OBJECTIVE Polygenic prediction of type 2 diabetes (T2D) in continental Africans is
adversely affected by the limited number of genome-wide association studies (GWAS) of …

Individuals with monogenic disorders can experience variable phenotypes that are
influenced by genetic variation. To investigate this in sickle cell disease (SCD), we …

Polygenic models have emerged as promising prediction tools for the prediction of complex
traits. Currently, the majority of polygenic models are developed in the context of predicting …

Previous studies have pointed out a link between vitamin D status and metabolic traits,
however, consistent evidence has not been provided yet. This cross-sectional study has …