Development of an improved blood-stage malaria vaccine targeting the essential RH5-CyRPA-RIPR invasion complex

BG Williams, LDW King, D Pulido, D Quinkert… - Nature …, 2024 - nature.com
Reticulocyte-binding protein homologue 5 (RH5), a leading blood-stage Plasmodium
falciparum malaria vaccine target, interacts with cysteine-rich protective antigen (CyRPA) …

A new landscape for malaria vaccine development

AJ Laurenson, MB Laurens - PLoS pathogens, 2024 - journals.plos.org
On October 6, 2021, the World Health Organization (WHO) recommended the first vaccine
against malaria to prevent Plasmodium falciparum malaria in children living in areas with …

Breadth of Fc-mediated effector function correlates with clinical immunity following human malaria challenge

IN Nkumama, R Ogwang, D Odera, F Musasia, K Mwai… - Immunity, 2024 - cell.com
Malaria is a life-threatening disease of global health importance, particularly in sub-Saharan
Africa. The growth inhibition assay (GIA) is routinely used to evaluate, prioritize, and quantify …