[HTML][HTML] Integration of multiple-omics data to reveal the shared genetic architecture of educational attainment, intelligence, cognitive performance, and Alzheimer's …

F Wang, H Wang, Y Yuan, B Han, S Qiu, Y Hu… - Frontiers in …, 2023 - frontiersin.org
Growing evidence suggests the effect of educational attainment (EA) on Alzheimer's disease
(AD), but less is known about the shared genetic architecture between them. Here …

[HTML][HTML] Mendelian randomization study supports the causal effects of air pollution on longevity via multiple age-related diseases

S Qiu, Y Hu, G Liu - npj Aging, 2023 - nature.com
Growing evidence suggests that exposure to fine particulate matter (PM2. 5) may reduce life
expectancy; however, the causal pathways of PM2. 5 exposure affecting life expectancy …

Genome-wide analysis reveals extensive genetic overlap between childhood phenotypes and later-life type 2 diabetes

S Qiu, Y Sun, J Guo, Y Zhang, Y Hu - Computers in Biology and Medicine, 2024 - Elsevier
Observational studies have indicated a potential influence of childhood phenotypes on the
later development of type 2 diabetes (T2D). However, the underlying biological mechanisms …

睡眠特征与骨关节炎发病风险: 两样本与多变量孟德尔随机化分析

陈继鑫, 余伟杰, 郭天赐, 周沁心, 牛朴钰, 叶云天… - 中国组织工程研究, 2024 - cjter.com
睡眠特征与骨关节炎发病风险:两样本与多变量孟德尔随机化分析 Page 1 Chinese Journal of
Tissue Engineering Research|Vol 28|No.32|November 2024|5203 中国组织工程研究 Chinese …

[HTML][HTML] Genetic determinants of Vitamin D deficiency in the Middle Eastern Qatari population: a genome-wide association study

NN Hendi, Y Al-Sarraj, UK Ismail Umlai, K Suhre… - Frontiers in …, 2023 - frontiersin.org
Introduction Epidemiological studies have consistently revealed that Vitamin D deficiency is
most prevalent in Middle Eastern countries. However, research on the impact of genetic loci …

基于孟德尔随机化分析躯干及下肢脂肪量与椎间盘退变的因果关系

杨敬言, 马涉, 黄仁俊, 王超逸, 赵余炀, 于栋 - 中国组织工程研究, 2024 - cjter.com
基于孟德尔随机化分析躯干及下肢脂肪量与椎间盘退变的因果关系 Page 1 5688|中国组织工程
研究|第28卷|第35期|2024年12月 中国组织工程研究 Chinese Journal of Tissue Engineering …

Sleep characteristics and risk of osteoarthritis: a two-sample and multivariate Mendelian randomization study

J Chen, W Yu, T Guo, Q Zhou, P Niu, Y Ye… - Chinese Journal of Tissue …, 2024 - cjter.com
BACKGROUND: In recent years, epidemiological studies have shown that sleep patterns
are risk factors for osteoarthritis, but the causal relationship between sleep characteristics …

A causal relationship between sleep behaviour and osteoporosis: a two-sample reverse-mediated Mendelian randomisation study

Y Wang, G Li, J Liu - 2024 - researchsquare.com
Background In recent years, there have been more and more clinical observational studies
on sleep behaviour and osteoporosis, but the causal relationship between sleep behaviour …

Bidirectional Mendelian randomization explores the causal relationship between arthritis and cerebral cortical volume

W Xu, M Ouyang, Z Jiang - 2024 - researchsquare.com
Background Mendelian randomization method was used to explore the causal relationship
between the occurrence of arthritis disease and volume changes in specific cerebral cortical …

Causal relationship between trunk and lower limb fat mass and intervertebral disc degeneration based on a Mendelian randomization analysis

J Yang, S Ma, R Huang, C Wang, Y Zhao… - Chinese Journal of Tissue …, 2024 - cjter.com
BACKGROUND: It has been found in recent observational studies that assessing localized
fat mass is crucial in the evaluation of disc degeneration. Although obesity has been …