Broadly neutralizing antibodies to SARS-CoV-2 and other human coronaviruses

Y Chen, X Zhao, H Zhou, H Zhu, S Jiang… - Nature Reviews …, 2023 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a recently emerged
pathogenic human coronavirus that belongs to the sarbecovirus lineage of the genus …

Vaccine adjuvants: mechanisms and platforms

T Zhao, Y Cai, Y Jiang, X He, Y Wei, Y Yu… - Signal transduction and …, 2023 - nature.com
Adjuvants are indispensable components of vaccines. Despite being widely used in
vaccines, their action mechanisms are not yet clear. With a greater understanding of the …

Monoclonal antibody therapies against SARS-CoV-2

D Focosi, S McConnell, A Casadevall… - The Lancet Infectious …, 2022 - thelancet.com
Monoclonal antibodies (mAbs) targeting the spike protein of SARS-CoV-2 have been widely
used in the ongoing COVID-19 pandemic. In this paper, we review the properties of mAbs …

A critical overview of current progress for COVID-19: development of vaccines, antiviral drugs, and therapeutic antibodies

M Kumari, RM Lu, MC Li, JL Huang, FF Hsu… - Journal of biomedical …, 2022 - Springer
The novel coronavirus disease (COVID-19) pandemic remains a global public health crisis,
presenting a broad range of challenges. To help address some of the main problems, the …

Bioactive compounds from Huashi Baidu decoction possess both antiviral and anti-inflammatory effects against COVID-19

H Xu, S Li, J Liu, J Cheng, L Kang… - Proceedings of the …, 2023 - National Acad Sciences
The coronavirus disease 2019 (COVID-19) pandemic is an ongoing global health concern,
and effective antiviral reagents are urgently needed. Traditional Chinese medicine theory …

Origin, virological features, immune evasion and intervention of SARS-CoV-2 Omicron sublineages

S Xia, L Wang, Y Zhu, L Lu, S Jiang - Signal Transduction and Targeted …, 2022 - nature.com
Recently, a large number of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) variants continuously emerged and posed a major threat to global public health. Among …

Challenges and developments in universal vaccine design against SARS-CoV-2 variants

F Zhao, X Zai, Z Zhang, J Xu, W Chen - npj Vaccines, 2022 - nature.com
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) had
become a global concern because of its unexpectedly high pathogenicity and …

STING agonist-derived LNP-mRNA vaccine enhances protective immunity against SARS-CoV-2

Y Zhang, J Yan, X Hou, C Wang, DD Kang, Y Xue… - Nano …, 2023 - ACS Publications
Lipid nanoparticle (LNP)-mediated delivery of messenger RNA (mRNA) COVID-19 vaccines
has provided large-scale immune protection to the public. To elicit a robust immune …

Adjuvant physiochemistry and advanced nanotechnology for vaccine development

H Ren, W Jia, Y Xie, M Yu, Y Chen - Chemical Society Reviews, 2023 - pubs.rsc.org
Vaccines comprising innovative adjuvants are rapidly reaching advanced translational
stages, such as the authorized nanotechnology adjuvants in mRNA vaccines against COVID …

Sensitivity to vaccines, therapeutic antibodies, and viral entry inhibitors and advances to counter the SARS-CoV-2 Omicron variant

H Zhou, M Møhlenberg, JC Thakor… - Clinical microbiology …, 2022 - Am Soc Microbiol
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) keeps evolving and
mutating into newer variants over time, which gain higher transmissibility, disease severity …