Stimulus‐Responsive Drug Delivery Nanoplatforms for Osteoarthritis Therapy

Q Jiang, S Zhang - Small, 2023 - Wiley Online Library
Osteoarthritis (OA) is one of the most prevalent age‐related degenerative diseases. With an
increasingly aging global population, greater numbers of OA patients are providing clear …

“Smart” Stimuli‐responsive Injectable Gels for Bone Tissue Engineering Application

H Li, Z Hao, S Zhang, B Li, Y Wang… - Macromolecular …, 2023 - Wiley Online Library
Bone grafting, as the current gold‐standard for large scaled bone damage of various
causes, has faced challenges from both the source and appliance. Emerging new tissue …

An antioxidant and antibacterial polydopamine-modified thermo-sensitive hydrogel dressing for Staphylococcus aureus-infected wound healing

P Ge, S Chang, T Wang, Q Zhao, G Wang, B He - Nanoscale, 2023 - pubs.rsc.org
Bacteria-infected wound healing is a complex and chronic process that poses a great threat
to human health. A thermo-sensitive hydrogel that undergoes a sol–gel transition at body …

Copper Nanodots‐Based Hybrid Hydrogels with Multiple Enzyme Activities for Acute and Infected Wound Repair

Y Cui, W Zhang, J Shan, J He, Q Niu… - Advanced …, 2024 - Wiley Online Library
Effectively controlling bacterial infection, reducing the inflammation and promoting vascular
regeneration are all essential strategies for wound repair. Nanozyme technology has …

[HTML][HTML] Combined ibuprofen-nanoconjugate micelles with E-selectin for effective sunitinib anticancer therapy

X Zeng, Y Teng, C Zhu, Z Li, T Liu, Y Sun… - International Journal of …, 2022 - ncbi.nlm.nih.gov
Methods We synthesized the sialic acid-poly (ethylene glycol)-ibuprofen (SA-PEG-IBU)
amphipathic conjugate in two-step reaction. The SA-PEG-IBU amphiphilic conjugates can …

Oral administration of live combined Bacillus subtilis and Enterococcus faecium alleviates colonic oxidative stress and inflammation in osteoarthritic rats by improving …

J Tang, X Song, M Zhao, H Chen, Y Wang… - Frontiers in …, 2022 - frontiersin.org
Osteoarthritis (OA) causes intestinal damage. The protective effect of probiotics on the
intestine is indeed effective; however, the mechanism of protection against intestinal …

Immune-regulating strategy against rheumatoid arthritis by inducing tolerogenic dendritic cells with modified zinc peroxide nanoparticles

H Qiao, J Mei, K Yuan, K Zhang, F Zhou, T Tang… - Journal of …, 2022 - Springer
In hypoxic dendritic cells (DCs), a low level of Zn2+ can induce the activation of
immunogenic DCs (igDCs), thereby triggering an active T-cell response to propel the …

[HTML][HTML] Chitosan-crosslinked polyvinyl alcohol anti-swelling hydrogel designed to prevent abdominal wall adhesion

Y Huang, J Zheng, G Zeng, H Xu, Y Lv, X Liang, L Jin… - Materials Today Bio, 2024 - Elsevier
Abdominal adhesion is a frequent clinical issue with a high incidence rate and
consequences following intra-abdominal surgery. Although many anti-adhesion materials …

Emerging Advances in Nanocarriers Approaches in the Effective Therapy of Pain Related Disorders: Recent Evidence and Futuristic Needs

N Chaurawal, M Kataria, MV Kumar, NP Mishra… - AAPS …, 2023 - Springer
Pain disorders are the primary cause of disability nowadays. These disorders, such as
rheumatoid arthritis (RA) and osteoarthritis (OA), cause loss of function, joint pain and …

Advances in local drug delivery technologies for improved rheumatoid arthritis therapy

X An, J Yang, X Cui, J Zhao, C Jiang, M Tang… - Advanced Drug Delivery …, 2024 - Elsevier
Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease characterized by
an inflammatory microenvironment and cartilage erosion within the joint cavity. Currently …