Type I interferons (IFNs) induce hundreds of IFN-stimulated genes (ISGs) in response to viral
infection. Induction of these ISGs must be regulated for an efficient and controlled antiviral …

Low back pain is tightly associated with intervertebral disc degeneration (IVDD) and
aberrant nucleus pulposus (NP) is a critical cause. miRNAs N6-methyladenosine (m6A) …

Messenger RNA (mRNA) vaccines have been studied for decades, but only recently, during
the COVID-19 pandemic, has the technology garnered noteworthy attention. In contrast to …

Testicular germ cell tumours (TGCTs) rank as the most common malignancy in men aged 20‐
34 years, and seminomas are the most type of TGCTs. As a crucial anti‐tumour agent with …

The alpha‐ketoglutarate‐dependent (ALKB) homolog 5 (ALKBH5), an m6A demethylase,
has been reported to be involved in the pathogenesis of preeclampsia (PE), but the exact …

Abstract Background Reactivation of Epstein Barr virus (EBV) leads to modulation of the viral
and cellular epitranscriptome. N6-methyladenosine (m6A) modification is a type of RNA …

Abstract Methyltransferase-like 3 (METTL3)-modulated N6-methyladenosine (m6A) was
recently identified as an important epigenetic regulation type during RNA processing and …

Cardiovascular diseases (CVDs) are the leading cause of morbidity and mortality in the
world. Despite considerable progress in the diagnosis, treatment and prognosis of CVDs …

Diabetic retinopathy (DR), a major microvascular complication of diabetes, affects most
diabetic individuals and has become the leading cause of vision loss. Metabolic memory …

Background LncRNAs are potential biomarkers for SLE, but the epigenetic regulatory
mechanisms of N6-methyladenosine (m6A) modification in SLE remain largely unclear …