[HTML][HTML] Transcriptome-wide analysis of RNA m6A methylation regulation of muscle development in Queshan Black pigs
Y Dou, Y Wei, Z Zhang, C Li, C Song, Y Liu, K Qi, X Li… - BMC genomics, 2023 - Springer
Abstract Background N6-methyladenosine (m6A) refers to the methylation modification of N6
position of RNA adenine, a dynamic reversible RNA epigenetic modification that plays an …
position of RNA adenine, a dynamic reversible RNA epigenetic modification that plays an …
[HTML][HTML] METTL3 regulates ossification of the posterior longitudinal ligament via the lncRNA XIST/miR-302a-3p/USP8 Axis
X Yuan, L Shi, Y Guo, J Sun, J Miao, J Shi… - Frontiers in Cell and …, 2021 - frontiersin.org
The prevalence of ossification of the posterior longitudinal ligament (OPLL) is increasing,
and currently there is no effective medical treatment for OPLL. Methyltransferase like 3 …
and currently there is no effective medical treatment for OPLL. Methyltransferase like 3 …
[HTML][HTML] Unveiling the methionine cycle: a key metabolic signature and NR4A2 as a methionine-responsive oncogene in esophageal squamous cell carcinoma
X Jin, L Liu, D Liu, J Wu, C Wang, S Wang… - Cell Death & …, 2024 - nature.com
Esophageal squamous cell carcinoma (ESCC) is a deadly malignancy with notable
metabolic reprogramming, yet the pivotal metabolic feature driving ESCC progression …
metabolic reprogramming, yet the pivotal metabolic feature driving ESCC progression …
[HTML][HTML] Physio-pathological effects of m6A modification and its potential contribution to melanoma
Y Liao, P Han, Y Zhang, B Ni - Clinical and Translational Oncology, 2021 - Springer
Methylation of N6-adenosine (m6A) is the most prevalent internal RNA modification and is
especially common among the messenger RNAs. These m6A modifications regulate …
especially common among the messenger RNAs. These m6A modifications regulate …
METTL3‐mediated m6A modification regulates the osteogenic differentiation through LncRNA CUTALP in periodontal mesenchymal stem cells of periodontitis …
X Chen, Y Qin, X Wang, H Lei, X Zhang… - Stem Cells …, 2024 - Wiley Online Library
Objective. Periodontitis is a chronic inflammatory disease that causes loss of periodontal
support tissue. Our objective was to investigate the mechanism by which METTL3‐mediated …
support tissue. Our objective was to investigate the mechanism by which METTL3‐mediated …
Regulating tumor microenvironments by a lymph node-targeting adjuvant via tumor-specific CTL-derived IFNγ
X Xu, C Yi, T Feng, Y Ge, M Liu, C Wu, H Yu, X Chen… - Clinical …, 2023 - Elsevier
Inducing tumor-specific T cell responses and regulating suppressive tumor
microenvironments have been a challenge for effective tumor therapy. CpG (ODN), the Toll …
microenvironments have been a challenge for effective tumor therapy. CpG (ODN), the Toll …
[HTML][HTML] Screening of key genes associated with m6A methylation in diabetic nephropathy patients by CIBERSORT and weighted gene coexpression network analysis
S Yin, W Li, J Wang, H Wu, J Hu… - American Journal of …, 2022 - ncbi.nlm.nih.gov
Diabetic nephropathy (DN) is a common complication of diabetes. Due to its complex
pathogenesis, there is no effective treatment. M6A is a newly discovered epigenetic …
pathogenesis, there is no effective treatment. M6A is a newly discovered epigenetic …
Molecular regulatory mechanisms underlying the adaptability of polyploid plants
M Scarrow, Y Wang, G Sun - Biological Reviews, 2021 - Wiley Online Library
Polyploidization influences the genetic composition and gene expression of an organism.
This multi‐level genetic change allows the formation of new regulatory pathways leading to …
This multi‐level genetic change allows the formation of new regulatory pathways leading to …
Integrated analysis of multi‐omics data on epigenetic changes caused by combined exposure to environmental hazards
SY Yu, EJ Koh, SH Kim, SY Lee, JS Lee… - Environmental …, 2021 - Wiley Online Library
Humans are easily exposed to environmentally hazardous factors in industrial sites or daily
life. In addition, exposure to various substances and not just one harmful substance is …
life. In addition, exposure to various substances and not just one harmful substance is …
[HTML][HTML] FTO/RUNX2 signaling axis promotes cementoblast differentiation under normal and inflammatory condition
Q Sun, T Zhao, B Li, M Li, P Luo, C Zhang… - … et Biophysica Acta (BBA …, 2022 - Elsevier
Abstract N 6-methyladenosine (m 6 A) is the most prevalent mRNA modification which plays
crucial roles in various biological processes, but its role in cementogenesis remains largely …
crucial roles in various biological processes, but its role in cementogenesis remains largely …