A comprehensive analysis based on histopathology, metabolomics and transcriptomics reveals molecular regulatory mechanisms of the red claw crayfish (Cherax …

D Chen, C Wang, L Guo, W Mo, Y Xin, H Cao, C Mu… - Aquaculture, 2022 - Elsevier
The maintenance of homeostasis is central for the survival of organisms under exposure to
various types of stress, toxicants, and pathogens, and small metabolites often play key roles …

“Feed a Cold, Starve a Fever?” A Review of Nutritional Strategies in the Setting of Bacterial Versus Viral Infections

S Sankararaman, C Venegas, S Seth… - Current Nutrition …, 2024 - Springer
Abstract Purpose of Review Some data, mostly originally derived from animal studies,
suggest that low glucose intake is protective in bacterial sepsis but detrimental in …

[HTML][HTML] Human tear metabolites associated with nucleoside-signalling pathways in bacterial keratitis

GS Shrestha, AK Vijay, F Stapleton, A White… - Experimental Eye …, 2023 - Elsevier
Objective The study aimed to profile and quantify tear metabolites associated with bacterial
keratitis using both untargeted and targeted metabolomic platforms. Methods Untargeted …

Transcriptome Profiling of Lung Innate Immune Responses Potentially Associated With the Pathogenesis of Acinetobacter baumannii Acute Lethal Pneumonia

X Zeng, H Gu, L Peng, Y Yang, N Wang, Y Shi… - Frontiers in …, 2020 - frontiersin.org
Acinetobacter baumannii is one of the dominating causes of nosocomial pneumonia,
however, very little is known about the host immune response associated with pathogenesis …

A novel laboratory-based nomogram for assessing infection presence risk in acute-on-chronic liver failure patients

R Sun, W Lu, W Ren, S Zhang, D Yao, N Zhang… - Scientific Reports, 2023 - nature.com
Accurate assessment of infection presence risk level, timely diagnosis, and effective control
are critical for decreasing mortality of Acute‑on‑chronic liver failure (ACLF). We aimed to …

Pervasive inflammatory activation in patients with deficiency in very‐long‐chain acyl‐coA dehydrogenase (VLCADD)

AN Vallejo, HJ Mroczkowski, JJ Michel… - Clinical & …, 2021 - Wiley Online Library
Objectives Very‐long‐chain acyl‐CoA dehydrogenase deficiency (VLCADD) is a disorder of
fatty acid oxidation. Symptoms are managed by dietary supplementation with medium‐chain …

[HTML][HTML] Immunological and metabolic characterization of environmental Mycobacterium chimaera infection in a murine model

SN Dawrs, R Virdi, MN Islam, NA Hasan, GJ Norton… - Microbes and …, 2023 - Elsevier
Mycobacterium chimaera causes pulmonary disease, but little is known of gradations in
isolate virulence. Previously, 17 M. chimaera isolates were screened for survival in THP1 …

Untargeted Metabolomic Analysis Reveals Plasma Differences between Mares with Endometritis and Healthy Ones

X Zhang, Y Gao, Z Mai, Y Li, J Wang, X Zhao, Y Zhang - Animals, 2024 - mdpi.com
Simple Summary Endometritis is a common reproductive system disease in mares that
severely threatens their fertility, causing significant economic losses. Currently, the clinical …

The model of aging acceleration network reveals the correlation of alzheimer's disease and aging at system level

M Zhou, X Xia, H Yan, S Li, S Bian… - BioMed research …, 2019 - Wiley Online Library
As the incidence of senile dementia continues to increase, researches on Alzheimer's
disease (AD) have become more and more important. Several studies have reported that …

Metabolomic and proteomic analyses of primary Sjogren's syndrome

J Zhang, Z Tang, Z Liu, G Wang, X Yang, X Hou - Immunobiology, 2023 - Elsevier
The pathogenesis of primary Sjogren's syndrome (pSS) has not been fully elucidated. We
explored differentially expressed proteins and metabolic pathways in pSS using proteomics …