Dry eye disease (DED) is the most common ocular surface disease, characterized by
insufficient production and/or instability of the tear film. Tear substitutes are usually the first …

Due to complicated anatomical and physical properties, targeted drug delivery to ocular
tissues continues to be a key challenge for formulation scientists. Various attempts are …

Ocular disorders comprising various diseases of the anterior and posterior segments are
considered as the main reasons for blindness. Natural products have been identified as …

Eye drops are ophthalmic formulations routinely used to treat dry eye. However, the low
ocular bioavailability is an obvious drawback of eye drops owing to short ocular retention …

Posterior segment diseases, such as age-related macular degeneration (AMD) and diabetic
retinopathy (DR) are vital factor that seriously threatens human vision health and quality of …

Liposomes are tiny lipid-based vesicles composed of one or more lipid bilayers, which
facilitate the encapsulation of hydrophilic, lipophilic, and amphiphilic biological active …

Ocular diseases profoundly impact patients' vision and overall quality of life globally.
However, effective ocular drug delivery presents formidable challenges within clinical …

Traditional eye drops are convenient to use; however, their effectiveness is limited by their
poor retention time and bioavailability in the eyes due to ocular barriers. Therefore …

The cornea is a remarkable tissue that possesses specialized structures designed to
safeguard the eye against foreign objects. However, its unique properties also make it …

Eye diseases and injuries constitute a significant clinical problem worldwide. Safe and
effective delivery of drugs to the eye is challenging mostly due to the presence of ocular …