The systemic inflammatory response syndrome (SIRS) after severe injury can lead to distant organ injury, multi-organ failure, and complications during recovery. Post-injury SIRS is …
YK Sun, C Wang, PQ Lin, L Hu, J Ye, ZG Gao… - World Journal of …, 2024 - Springer
Abstract Background Coronavirus disease 2019 (COVID-19) tends to have mild presentations in children. However, severe and critical cases do arise in the pediatric …
The US Food and Drug Administration (FDA) has recently approved colchicine to reduce the risk of myocardial infarction (MI), stroke, coronary revascularization, and cardiovascular (CV) …
T Grewal, MKL Nguyen, C Buechler - Life Science Alliance, 2024 - life-science-alliance.org
The rapid development of vaccines to combat severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections has been critical to reduce the severity of COVID-19 …
Inflammation has played a pivotal role in atherosclerosis and other cardiovascular disorders, prompting the exploration of anti-inflammatory therapies to improve cardiovascular …
AS Eustes, A Ahmed, J Swamy, G Patil… - Journal of Thrombosis …, 2024 - Elsevier
Background COVID-19 can cause profound inflammation and coagulopathy, and while many mechanisms have been proposed, there is no known common pathway leading to a …
S Hu, T Lin, Y Chen, Y Guo, X Sun… - The Journal of Gene …, 2024 - Wiley Online Library
Background Acute pancreatitis (AP) is a potentially lethal acute disease highly involved in coagulation disorders. Pyroptosis has been reported to exacerbate coagulation disorders …
F Liew, C Efstathiou, S Fontanella, M Richardson… - medRxiv, 2023 - medrxiv.org
One in ten SARS-CoV-2 infections result in prolonged symptoms termed 'long COVID', yet disease phenotypes and mechanisms are poorly understood. We studied the blood …