CD36 mediates SARS-CoV-2-envelope-protein-induced platelet activation and thrombosis

Z Tang, Y Xu, Y Tan, H Shi, P Jin, Y Li, J Teng… - Nature …, 2023 - nature.com
Aberrant coagulation and thrombosis are associated with severe COVID-19 post-SARS-CoV-
2 infection, yet the underlying mechanism remains obscure. Here we show that serum levels …

The intersection of coagulation activation and inflammation after injury: What you need to know

TW Costantini, LZ Kornblith, T Pritts… - Journal of Trauma and …, 2023 - journals.lww.com
The systemic inflammatory response syndrome (SIRS) after severe injury can lead to distant
organ injury, multi-organ failure, and complications during recovery. Post-injury SIRS is …

Severe pediatric COVID-19: a review from the clinical and immunopathophysiological perspectives

YK Sun, C Wang, PQ Lin, L Hu, J Ye, ZG Gao… - World Journal of …, 2024 - Springer
Abstract Background Coronavirus disease 2019 (COVID-19) tends to have mild
presentations in children. However, severe and critical cases do arise in the pediatric …

Colchicine for cardiovascular prevention: the dawn of a new era has finally come

A Bonaventura, A Abbate - 2023 - academic.oup.com
The US Food and Drug Administration (FDA) has recently approved colchicine to reduce the
risk of myocardial infarction (MI), stroke, coronary revascularization, and cardiovascular (CV) …

Cholesterol and COVID-19—therapeutic opportunities at the host/virus interface during cell entry

T Grewal, MKL Nguyen, C Buechler - Life Science Alliance, 2024 - life-science-alliance.org
The rapid development of vaccines to combat severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) infections has been critical to reduce the severity of COVID-19 …

Role of Colchicine in Cardiovascular Disorders

E Moras, L Subramanian, F Romeo, K Gandhi… - Cardiology in …, 2024 - journals.lww.com
Inflammation has played a pivotal role in atherosclerosis and other cardiovascular disorders,
prompting the exploration of anti-inflammatory therapies to improve cardiovascular …

Extracellular histones: a unifying mechanism driving platelet-dependent extracellular vesicle release and thrombus formation in COVID-19

AS Eustes, A Ahmed, J Swamy, G Patil… - Journal of Thrombosis …, 2024 - Elsevier
Background COVID-19 can cause profound inflammation and coagulopathy, and while
many mechanisms have been proposed, there is no known common pathway leading to a …

NLRC4‐mediated pyroptosis was involved in coagulation disorders of acute pancreatitis

S Hu, T Lin, Y Chen, Y Guo, X Sun… - The Journal of Gene …, 2024 - Wiley Online Library
Background Acute pancreatitis (AP) is a potentially lethal acute disease highly involved in
coagulation disorders. Pyroptosis has been reported to exacerbate coagulation disorders …

Пандемия коронавирусной болезни 2019 (COVID-19) и аутоиммунные ревматические заболевания: итоги и перспективы

ЕЛ Насонов - Научно-практическая ревматология, 2024 - rsp.mediar-press.net
Аннотация Пандемия коронавирусной болезни 2019 (COVID-19, coronavirus disease
2019), этиологически связанной с вирусом SARS-CoV-2 (severe acute respiratory …

Large scale phenotyping of long COVID inflammation reveals mechanistic subtypes of disease

F Liew, C Efstathiou, S Fontanella, M Richardson… - medRxiv, 2023 - medrxiv.org
One in ten SARS-CoV-2 infections result in prolonged symptoms termed 'long COVID', yet
disease phenotypes and mechanisms are poorly understood. We studied the blood …