Nonalcoholic steatohepatitis-related hepatocellular carcinoma: pathogenesis and treatment

JM Llovet, CE Willoughby, AG Singal… - Nature reviews …, 2023 - nature.com
Nonalcoholic fatty liver disease (NAFLD), including its more severe manifestation,
nonalcoholic steatohepatitis (NASH), has a global prevalence of 20–25% and is a major …

The clinical management of hepatocellular carcinoma worldwide: A concise review and comparison of current guidelines: 2022 update

N Wen, Y Cai, F Li, H Ye, W Tang, P Song… - Bioscience …, 2022 - jstage.jst.go.jp
Hepatocellular carcinoma (HCC) is the fifth most common malignancy and the second
leading cause of cancer-related mortality worldwide. This review is an updated version that …

AASLD practice guidance on prevention, diagnosis, and treatment of hepatocellular carcinoma

AG Singal, JM Llovet, M Yarchoan, N Mehta… - Hepatology, 2023 - journals.lww.com
This guidance document provides an updated approach to the prevention, diagnosis, and
treatment of hepatocellular carcinoma (HCC). The prior American Association for the Study …

[HTML][HTML] Exposure to perfluoroalkyl substances and risk of hepatocellular carcinoma in a multiethnic cohort

JA Goodrich, D Walker, X Lin, H Wang, T Lim… - JHEP Reports, 2022 - Elsevier
Background & Aims Exposure to poly-and perfluoroalkyl substances (PFAS), a class of
persistent organic pollutants, is ubiquitous. Animal studies suggest that PFAS may increase …

[HTML][HTML] MAFLD enhances clinical practice for liver disease in the Asia-Pacific region

T Kawaguchi, T Tsutsumi, D Nakano… - Clinical and …, 2022 - ncbi.nlm.nih.gov
Fatty liver is now a major cause of liver disease in the Asia-Pacific region. Liver diseases in
this region have distinctive characteristics. First, fatty liver is frequently observed in …

Hepatocellular carcinoma surveillance—Utilization, barriers and the impact of changing aetiology

DQ Huang, AG Singal, F Kanwal… - Nature Reviews …, 2023 - nature.com
Hepatocellular carcinoma (HCC) is the third leading cause of cancer death worldwide.
Surveillance for HCC is critical for early detection and treatment, but fewer than one-quarter …

Hepatocellular carcinoma in chronic viral hepatitis: where do we stand?

FP Russo, A Zanetto, E Pinto, S Battistella… - International journal of …, 2022 - mdpi.com
Hepatocellular carcinoma (HCC) is one of the major causes of cancer-related death.
Although the burden of alcohol-and NASH-related HCC is growing, chronic viral hepatitis …

Epidemiologic, genetic, pathogenic, metabolic, epigenetic aspects involved in NASH-HCC: current therapeutic strategies

J Gutiérrez-Cuevas, S Lucano-Landeros… - Cancers, 2022 - mdpi.com
Simple Summary Hepatocellular carcinoma (HCC) is an aggressive human cancer and is
caused as consequences of chronic liver diseases. Although HCC is more common in …

[HTML][HTML] Bifidobacterium pseudolongum-generated acetate suppresses non-alcoholic fatty liver disease-associated hepatocellular carcinoma

Q Song, X Zhang, W Liu, H Wei, W Liang, Y Zhou… - Journal of …, 2023 - Elsevier
Background & Aims Recent studies have highlighted the role of the gut microbiota and their
metabolites in non-alcoholic fatty liver disease-associated hepatocellular carcinoma …

[HTML][HTML] Epidemiological characteristics of primary liver cancer in mainland China from 2003 to 2020: A representative multicenter study

J Lin, H Zhang, H Yu, X Bi, W Zhang, J Yin… - Frontiers in …, 2022 - frontiersin.org
Background: The contribution of hepatitis B virus (HBV) and hepatitis C virus (HCV) to
primary liver cancer (PLC) and their association with cancer aggressiveness remains …