[HTML][HTML] An introduction to the Marburg virus vaccine consortium, MARVAC

RW Cross, IM Longini, S Becker, K Bok… - PLoS …, 2022 - journals.plos.org
The emergence of Marburg virus (MARV) in Guinea and Ghana triggered the assembly of
the MARV vaccine “MARVAC” consortium representing leaders in the field of vaccine …

[HTML][HTML] Emergence of Marburg virus: a global perspective on fatal outbreaks and clinical challenges

S Srivastava, D Sharma, S Kumar, A Sharma… - Frontiers in …, 2023 - frontiersin.org
The Marburg virus (MV), identified in 1967, has caused deadly outbreaks worldwide, the
mortality rate of Marburg virus disease (MVD) varies depending on the outbreak and virus …

[HTML][HTML] Species-specific immunogenicity and protective efficacy of a vesicular stomatitis virus-based Sudan virus vaccine: a challenge study in macaques

A Marzi, P Fletcher, F Feldmann, G Saturday… - The Lancet …, 2023 - thelancet.com
Summary Background The recent Sudan virus (SUDV) outbreak in Uganda highlights the
need for rapid response capabilities, including development of vaccines against emerging …

[HTML][HTML] A recombinant VSV-vectored vaccine rapidly protects nonhuman primates against heterologous lethal Lassa fever

RW Cross, C Woolsey, AN Prasad, V Borisevich… - Cell reports, 2022 - cell.com
Lassa virus (LASV) is recognized by the World Health Organization as one of the top five
pathogens likely to cause a severe outbreak. A recent unprecedented resurgence of LASV …

Marburg virus disease: a deadly rare virus is coming

F Zhao, Y He, H Lu - Bioscience trends, 2022 - jstage.jst.go.jp
Two cases of the deadly Marburgvirus were reported in Ghana, which might be a new global
virus alert following COVID-19 and novel monkeypox. Thus far, there is no vaccine or …

A single-shot ChAd3-MARV vaccine confers rapid and durable protection against Marburg virus in nonhuman primates

R Hunegnaw, AN Honko, L Wang, D Carr… - Science translational …, 2022 - science.org
Marburg virus (MARV) causes a severe hemorrhagic fever disease in primates with mortality
rates in humans of up to 90%. MARV has been identified as a category A bioterrorism agent …

[HTML][HTML] A highly attenuated Vesiculovax vaccine rapidly protects nonhuman primates against lethal Marburg virus challenge

C Woolsey, RW Cross, KN Agans… - PLoS neglected …, 2022 - journals.plos.org
Background Marburg virus (MARV), an Ebola-like virus, remains an eminent threat to public
health as demonstrated by its high associated mortality rate (23–90%) and recent …

[HTML][HTML] Rapid protection of nonhuman primates against Marburg virus disease using a single low-dose VSV-based vaccine

KL O'Donnell, F Feldmann, B Kaza, CS Clancy… - …, 2023 - thelancet.com
Background Marburg virus (MARV) is the causative agent of Marburg virus disease (MVD)
which has a case fatality rate up to∼ 90% in humans. Recently, there were cases reported …

Praemonitus praemunitus: can we forecast and prepare for future viral disease outbreaks?

Z Sessions, T Bobrowski, HJ Martin… - FEMS Microbiology …, 2023 - academic.oup.com
Understanding the origins of past and present viral epidemics is critical in preparing for
future outbreaks. Many viruses, including SARS-CoV-2, have led to significant …

A highly attenuated panfilovirus VesiculoVax vaccine rapidly protects nonhuman primates against Marburg virus and 3 species of Ebola virus

C Woolsey, V Borisevich, KN Agans… - The Journal of …, 2023 - academic.oup.com
Abstract Background The family Filoviridae consists of several virus members known to
cause significant mortality and disease in humans. Among these, Ebola virus (EBOV) …