Written by Caleb Finch, one of the leading scientists of our time, The Biology of Human
Longevity: Inflammation, Nutrition, and Aging in the Evolution of Lifespans synthesizes …

This article investigates the fertility of Danish twins born during the periods 1870–1910 and
1953–64 in order to pursue two central questions for understanding human reproduction: Do …

Exceptional longevity represents an extreme phenotype. Current centenarians are survivors
of a cohort who display delayed onset of age-related diseases and/or resistance to …

Background Prospective data on nongenetic determinants of exceptional longevity are
limited, and information on long-lived men and their functional status is particularly sparse …

Neither genetic nor environmental factors fully account for variability in individual longevity:
genetically identical invertebrates in homogenous environments often experience no less …

Genetic factors clearly contribute to exceptional longevity and healthy aging in humans, yet
the identification of the underlying genes remains a challenge. Longevity is a complex …

Heritability is the proportion of phenotypic variation in a population that is attributable to
genetic variation among individuals. Many ophthalmic disorders and biometric traits are …

Background Overt hyperthyroidism has been associated with cardiac arrhythmias,
hypercoagulopathy, stroke, and pulmonary embolism, all of which may increase mortality …

Background: The aging phenotype in humans is very heterogeneous and can be described
as a complex mosaic resulting from the interaction of a variety of environmental, stochastic …

A number of indices exist to calculate lifespan variation, each with different underlying
properties. Here, we present new formulae for the response of seven of these indices to …