Three dimensions of the survival curve: Horizontalization, verticalization, and longevity extension
Three dimensions of the survival curve have been developed:(1)“horizontalization,” which
corresponds to how long a cohort and how many survivors can live before aging-related …
corresponds to how long a cohort and how many survivors can live before aging-related …
[图书][B] Aging: The social context
L Morgan, S Kunkel - 2001 - books.google.com
Page 1 SECOND EDITION AGING • THE SOCIAL CONTEXT Leslie Morgan Suzanne Kunkel
Page 2 Page 3 AGING THE SOCIAL CONTEXT Second Edition This One EFTL-227-UURT …
Page 2 Page 3 AGING THE SOCIAL CONTEXT Second Edition This One EFTL-227-UURT …
Gender-specific association between− 1082 IL-10 promoter polymorphism and longevity
D Lio, L Scola, A Crivello, G Colonna-Romano… - Genes & …, 2002 - nature.com
Ageing is characterized by a pro-inflammatory status, which could contribute to the onset of
major age-related diseases. Thus, genetic variations in pro-or anti-inflammatory cytokines …
major age-related diseases. Thus, genetic variations in pro-or anti-inflammatory cytokines …
Metagenomic and metabolomic remodeling in nonagenarians and centenarians and its association with genetic and socioeconomic factors
Q Xu, C Wu, Q Zhu, R Gao, J Lu, M Valles-Colomer… - Nature Aging, 2022 - nature.com
A better understanding of the biological and environmental variables that contribute to
exceptional longevity has the potential to inform the treatment of geriatric diseases and help …
exceptional longevity has the potential to inform the treatment of geriatric diseases and help …
The genetics of human longevity: an intricacy of genes, environment, culture and microbiome
Approximately one-quarter of the variation in lifespan in developed countries can be
attributed to genetic factors. However, even large population based studies investigating …
attributed to genetic factors. However, even large population based studies investigating …
Polyunsaturated fats, membrane lipids and animal longevity
AJ Hulbert, MA Kelly, SK Abbott - Journal of Comparative Physiology B, 2014 - Springer
Fatty acids are essential for life because they are essential components of cellular
membranes. Lower animals can synthesize all four classes of fatty acids from non-lipid …
membranes. Lower animals can synthesize all four classes of fatty acids from non-lipid …
Aging biomarkers: from functional tests to multi‐omics approaches
Aging results in various deleterious changes in the human body that may lead to loss of
function and the manifestation of chronic diseases. While diseases can generally be reliably …
function and the manifestation of chronic diseases. While diseases can generally be reliably …
Midlife muscle strength and human longevity up to age 100 years: a 44-year prospective study among a decedent cohort
T Rantanen, K Masaki, Q He, GW Ross, BJ Willcox… - Age, 2012 - Springer
We studied prospectively the midlife handgrip strength, living habits, and parents' longevity
as predictors of length of life up to becoming a centenarian. The participants were 2,239 …
as predictors of length of life up to becoming a centenarian. The participants were 2,239 …
Rare genetic coding variants associated with human longevity and protection against age-related diseases
Extreme longevity in humans has a strong genetic component, but whether this involves
genetic variation in the same longevity pathways as found in model organisms is unclear …
genetic variation in the same longevity pathways as found in model organisms is unclear …
Replication of an association of variation in the FOXO3A gene with human longevity using both case–control and longitudinal data
Genetic variation in FOXO3A has previously been associated with human longevity. Studies
published so far have been case–control studies and hence vulnerable to bias introduced …
published so far have been case–control studies and hence vulnerable to bias introduced …