An overview of DNA methylation markers for early detection of gastric cancer: current status, challenges, and prospects

Y Xue, C Huang, B Pei, ZZ Wang, Y Dai - Frontiers in genetics, 2023 - frontiersin.org
Background: Gastric cancer (GC) is one of the most common malignancies, with a low 5-
year survival rate. However, if diagnosed at an early stage, it can be cured by endoscopic …

Malignancies in patients with celiac disease: Diagnostic challenges and molecular advances

M Ivanova, L Bottiglieri, E Sajjadi, K Venetis, N Fusco - Genes, 2023 - mdpi.com
Celiac disease (CD) is a multiorgan autoimmune disorder of the chronic intestinal disease
group characterized by duodenal inflammation in genetically predisposed individuals …

[HTML][HTML] A sensitive and robust plasma-based DNA methylation panel for early detection of target gastrointestinal cancers

Y Dai, H Li, Q Wu, J Wang, K Wang, S Fei, B Pei… - Neoplasia, 2023 - Elsevier
Abstract Background Target gastrointestinal cancers (GICs), encompassing esophageal
cancer (EC), gastric cancer (GC), and colorectal cancer (CRC), originate within a single …

DNA methylation markers in esophageal cancer

Y Xu, Z Wang, B Pei, J Wang, Y Xue, G Zhao - Frontiers in Genetics, 2024 - frontiersin.org
Background Esophageal cancer (EC) is a prevalent malignancy characterized by a low 5-
year survival rate, primarily attributed to delayed diagnosis and limited therapeutic options …

Effects of DNA methylation and its application in inflammatory bowel disease

FA Akanyibah, Y Zhu, A Wan… - International …, 2024 - spandidos-publications.com
Inflammatory bowel disease (IBD) is marked by persistent inflammation, and its development
and progression are linked to environmental, genetic, immune system and gut microbial …

One-step reverse transcriptase-free miRNA detection system and its application for detection of gastrointestinal cancers

G Zhao, Y Xue, Y Dai, X Zhou, H Li, G Sheng, H Xu… - Talanta, 2024 - Elsevier
MicroRNAs (miRNAs) play pivotal roles in gene regulation and their dysregulation is
implicated in various diseases, including cancer. Current methods for miRNA analysis often …

The signature of cancer methylation markers in maternal plasma: Factors influencing the development and application of cancer liquid biopsy assay

Y Xue, G Zhao, L Song, L Qiao, C Huang, K Wang… - Gene, 2024 - Elsevier
Background DNA methylation is highly correlated with cancer and embryo development,
and plasma-based methylation markers have been widely used for cancer early detection …