Structural biology of SARS-CoV-2: open the door for novel therapies

W Yan, Y Zheng, X Zeng, B He, W Cheng - Signal Transduction and …, 2022 - nature.com
Abstract Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is the causative
agent of the pandemic disease COVID-19, which is so far without efficacious treatment. The …

Drug repurposing approach to fight COVID-19

TU Singh, S Parida, MC Lingaraju, M Kesavan… - Pharmacological …, 2020 - Springer
Currently, there are no treatment options available for the deadly contagious disease,
coronavirus disease 2019 (COVID-19). Drug repurposing is a process of identifying new …

An updated review of computer‐aided drug design and its application to COVID‐19

AB Gurung, MA Ali, J Lee, MA Farah… - BioMed research …, 2021 - Wiley Online Library
The recent outbreak of the deadly coronavirus disease 19 (COVID‐19) pandemic poses
serious health concerns around the world. The lack of approved drugs or vaccines continues …

COVID-19 and therapy with essential oils having antiviral, anti-inflammatory, and immunomodulatory properties

M Asif, M Saleem, M Saadullah, HS Yaseen… - …, 2020 - Springer
Abstract Coronavirus disease of 2019 (COVID-19) has emerged as a global health threat.
Unfortunately, there are very limited approved drugs available with established efficacy …

Using X-ray images and deep learning for automated detection of coronavirus disease

K El Asnaoui, Y Chawki - Journal of Biomolecular Structure and …, 2021 - Taylor & Francis
Coronavirus is still the leading cause of death worldwide. There are a set number of COVID-
19 test units accessible in emergency clinics because of the expanding cases daily …

Evaluation of green tea polyphenols as novel corona virus (SARS CoV-2) main protease (Mpro) inhibitors – an in silico docking and molecular dynamics simulation …

R Ghosh, A Chakraborty, A Biswas… - Journal of Biomolecular …, 2021 - Taylor & Francis
Abstract Coronavirus disease 2019 (COVID-19) is a viral respiratory disease which caused
global health emergency and announced as pandemic disease by World Health …

Targeting SARS-CoV-2 spike protein of COVID-19 with naturally occurring phytochemicals: an in silico study for drug development

P Pandey, JS Rane, A Chatterjee, A Kumar… - Journal of …, 2021 - Taylor & Francis
Spike glycoprotein, a class I fusion protein harboring the surface of SARS-CoV-2 (SARS-
CoV-2S), plays a seminal role in the viral infection starting from recognition of the host cell …

Efficacy of favipiravir in COVID-19 treatment: a multi-center randomized study

HM Dabbous, S Abd-Elsalam, MH El-Sayed… - Archives of …, 2021 - Springer
No specific antiviral drugs have been approved for the treatment of COVID-19. This study
aimed to evaluate the efficacy of favipiravir in treatment of COVID-19. This was a multicenter …

Identification of phytochemical inhibitors against main protease of COVID-19 using molecular modeling approaches

A Kumar, G Choudhir, SK Shukla… - Journal of …, 2021 - Taylor & Francis
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a novel corona virus that
causes corona virus disease 2019 (COVID-19). The COVID-19 rapidly spread across the …

RNA-dependent RNA polymerase: Structure, mechanism, and drug discovery for COVID-19

Y Jiang, W Yin, HE Xu - Biochemical and biophysical research …, 2021 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus-2 (SARS-CoV-2) has rapidly become a global pandemic. Although …