The COVID-19 pandemic and Alzheimer's disease: mutual risks and mechanisms

F Chen, Y Chen, Y Wang, Q Ke, L Cui - Translational neurodegeneration, 2022 - Springer
Abstract Coronavirus disease 2019 (COVID-19), which is caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), is a life-threatening disease, especially …

Alzheimer's disease and COVID-19: Interactions, intrinsic linkages, and the role of immunoinflammatory responses in this process

W Li, L Sun, L Yue, S Xiao - Frontiers in immunology, 2023 - frontiersin.org
Alzheimer's disease (AD) and COVID-19 share many common risk factors, such as
advanced age, complications, APOE genotype, etc. Epidemiological studies have also …

SARS-CoV-2 invasion and pathological links to prion disease

WJ Lukiw, VR Jaber, AI Pogue, Y Zhao - Biomolecules, 2022 - mdpi.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of the
COVID-19 disease, is a highly infectious and transmissible viral pathogen that continues to …

Infection with COVID‐19 is no longer a public emergency: But what about degenerative dementia?

B Yulug, B Ayyıldız, S Ayyıldız… - Journal of Medical …, 2023 - Wiley Online Library
Although no longer considered a public health threat, post‐COVID cognitive syndrome
continues to impact on a considerable proportion of individuals who were infected with …

NLRP3 Inflammasome's Activation in Acute and Chronic Brain Diseases—An Update on Pathogenetic Mechanisms and Therapeutic Perspectives with Respect to …

A Chiarini, L Gui, C Viviani, U Armato, I Dal Prà - Biomedicines, 2023 - mdpi.com
Increasingly prevalent acute and chronic human brain diseases are scourges for the elderly.
Besides the lack of therapies, these ailments share a neuroinflammation that is …

SARS-CoV-2, long COVID, prion disease and neurodegeneration

Y Zhao, VR Jaber, WJ Lukiw - Frontiers in Neuroscience, 2022 - frontiersin.org
On the last day of the year 2019 a novel Betacoronavirus (2019-nCov), now known as
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and causing the highly …

miRNAs as a potential biomarker in the COVID-19 infection and complications course, severity, and outcome

M Jankovic, D Nikolic, I Novakovic, B Petrovic… - Diagnostics, 2023 - mdpi.com
During the last three years, since the emergence of the COVID-19 pandemic, a significant
number of scientific publications have focused on resolving susceptibility to the infection, as …

Does SARS-CoV-2 affect neurodegenerative disorders? TLR2, a potential receptor for SARS-CoV-2 in the CNS

MP Szabo, M Iba, A Nath, E Masliah… - Experimental & Molecular …, 2022 - nature.com
Abstract The coronavirus (COVID-19) pandemic, caused by severe acute respiratory system
coronavirus 2 (SARS-CoV-2), has created significant challenges for scientists seeking to …

microRNA, the innate-immune system and SARS-CoV-2

JM Hill, WJ Lukiw - Frontiers in Cellular and Infection Microbiology, 2022 - frontiersin.org
The single-stranded viral RNA (ssvRNA) known as the severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) that causes COVID-19 can be effectively inactivated by a …

Links between COVID-19 and Alzheimer's disease—what do we already know?

E Rudnicka-Drożak, P Drożak, G Mizerski… - International Journal of …, 2023 - mdpi.com
Alzheimer's disease (AD) is a life-changing condition whose etiology is explained by several
hypotheses. Recently, a new virus contributed to the evidence of viral involvement in AD: the …