[HTML][HTML] Novel insights into STAT3 in renal diseases

J Yu, S Fan, X Li, R Hou, X Hu, J Wang, R Shan… - Biomedicine & …, 2023 - Elsevier
Signal transducer and activator of transcription 3 (STAT3) is a cell-signal transcription factor
that has attracted considerable attention in recent years. The stimulation of cytokines and …

Differentially‐regulated miRNAs in COVID‐19: A systematic review

W Ahmad, B Gull, J Baby, NG Panicker… - Reviews in Medical …, 2023 - Wiley Online Library
Severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2) is responsible for
coronavirus disease of 2019 (COVID‐19) that infected more than 760 million people …

[HTML][HTML] SARS-CoV-2 viral protein ORF3A injures renal tubules by interacting with TRIM59 to induce STAT3 activation

H Cai, Y Chen, Y Feng, M Asadi, L Kaufman, K Lee… - Molecular Therapy, 2023 - cell.com
Acute kidney injury occurs frequently in COVID-19 patients infected by the coronavirus
SARS-CoV-2, and infection of kidney cells by this virus has been reported. However, little is …

[HTML][HTML] Immune-mediated inflammatory responses of alveolar epithelial cells: Implications for COVID-19 lung pathology

A Barilli, R Visigalli, F Ferrari, MG Bianchi, V Dall'Asta… - Biomedicines, 2022 - mdpi.com
Background. Clinical and experimental evidence point to a dysregulated immune response
caused by SARS-CoV-2 as the primary mechanism of lung disease in COVID-19. However …

Prostaglandins and non-steroidal anti-inflammatory drugs in Covid-19

HM Al-Kuraishy, AI Al-Gareeb… - Biotechnology and …, 2022 - Taylor & Francis
In response to different viral infections, including SARS-CoV-2 infection, pro-inflammatory,
anti-inflammatory cytokines, and bioactive lipids are released from infected and immune …

Immunosuppressants exert differential effects on pan‐coronavirus infection and distinct combinatory antiviral activity with molnupiravir and nirmatrelvir

Y Wang, P Li, M Lavrijsen, RJ Rottier… - United European …, 2023 - Wiley Online Library
Background Immunocompromised populations, such as organ transplant recipients and
patients with inflammatory bowel disease (IBD) receiving immunosuppressive …

[HTML][HTML] Inhibition of Toll-like receptor 4 and Interleukin-1 receptor prevent SARS-CoV-2 mediated kidney injury

D Nakazawa, Y Takeda, M Kanda, U Tomaru… - Cell Death …, 2023 - nature.com
Acute kidney injury (AKI) is a common and severe complication of the coronavirus disease
2019 (COVID-19). Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) directly …

[HTML][HTML] Identification of hub genes associated with acute kidney injury induced by renal ischemia–reperfusion injury in mice

S He, L He, F Yan, J Li, X Liao, M Ling, R Jing… - Frontiers in …, 2022 - frontiersin.org
Background: Acute kidney injury (AKI) is a severe clinical syndrome, and ischemia–
reperfusion injury is an important cause of acute kidney injury. The aim of the present study …

Postmortem Histopathologic Findings and SARS-CoV-2 Detection in Autopsy Kidneys of Patients With COVID-19: A Systematic Review and Meta-Analysis

M Mahjani, M Parvin, S Ghobadi, A Jafari… - American Journal of …, 2023 - academic.oup.com
Objectives This systematic review and meta-analysis aimed to investigate the prevalence of
postmortem kidney histopathologic features of patients with coronavirus disease 2019 …

[HTML][HTML] Proteomic snapshot of saliva samples predicts new pathways implicated in SARS-CoV-2 pathogenesis

E Moreno, S Ciordia, SM Fátima, D Jiménez… - Clinical Proteomics, 2024 - Springer
Background Information on the microbiome's human pathways and active members that can
affect SARS-CoV-2 susceptibility and pathogenesis in the salivary proteome is very scarce …