Epithelial tight junctions define the paracellular permeability of the intestinal barrier.
Molecules can cross the tight junctions via two distinct size-selective and charge-selective …

The intestinal barrier protects the host against gut microbes, food antigens, and toxins
present in the gastrointestinal tract. However, gut barrier integrity can be affected by intrinsic …

The intestinal epithelial tight junction (TJ) barrier controls the paracellular permeation of
contents from the intestinal lumen into the intestinal tissue and systemic circulation. A …

The objectives of this review on 'leaky gut'for clinicians are to discuss the components of the
intestinal barrier, the diverse measurements of intestinal permeability, their perturbation in …

An increased intestinal permeability has been described in various gastrointestinal and non-
gastrointestinal disorders. Nevertheless, the concept and definition of intestinal permeability …

Background & Aims Increased intestinal permeability has been associated with Crohn's
disease (CD), but it is not clear whether it is a cause or result of the disease. We performed a …

Abstract The 2 nd International Conference on Controversies in Vitamin D was held in
Monteriggioni (Siena), Italy, September 11-14, 2018. The aim of this meeting was to address …

The gut microbiota has an important role in the gut barrier, inflammation and metabolic
functions. Studies have identified a close association between the intestinal barrier and …

A fundamental function of the intestinal epithelium is to act as a barrier that limits interactions
between luminal contents such as the intestinal microbiota, the underlying immune system …

The intestinal epithelial lining, together with factors secreted from it, forms a barrier that
separates the host from the environment. In pathologic conditions, the permeability of the …