[HTML][HTML] Exploitation of glycosylation in enveloped virus pathobiology
Y Watanabe, TA Bowden, IA Wilson… - Biochimica et Biophysica …, 2019 - Elsevier
Glycosylation is a ubiquitous post-translational modification responsible for a multitude of
crucial biological roles. As obligate parasites, viruses exploit host-cell machinery to …
crucial biological roles. As obligate parasites, viruses exploit host-cell machinery to …
[HTML][HTML] The scavenger function of liver sinusoidal endothelial cells in health and disease
The aim of this review is to give an outline of the blood clearance function of the liver
sinusoidal endothelial cells (LSECs) in health and disease. Lining the hundreds of millions …
sinusoidal endothelial cells (LSECs) in health and disease. Lining the hundreds of millions …
Site-specific glycan analysis of the SARS-CoV-2 spike
The emergence of the betacoronavirus, severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19), represents a …
(SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19), represents a …
[HTML][HTML] SARS-CoV-2 escape in vitro from a highly neutralizing COVID-19 convalescent plasma
E Andreano, G Piccini, D Licastro, L Casalino… - BioRxiv, 2020 - ncbi.nlm.nih.gov
To investigate the evolution of SARS-CoV-2 in the immune population, we co-incubated
authentic virus with a highly neutralizing plasma from a COVID-19 convalescent patient. The …
authentic virus with a highly neutralizing plasma from a COVID-19 convalescent patient. The …
SARS-CoV-2 escape from a highly neutralizing COVID-19 convalescent plasma
E Andreano, G Piccini, D Licastro… - Proceedings of the …, 2021 - National Acad Sciences
To investigate the evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) in the immune population, we coincupi bated the authentic virus with a highly neutralizing …
2) in the immune population, we coincupi bated the authentic virus with a highly neutralizing …
[HTML][HTML] Vulnerabilities in coronavirus glycan shields despite extensive glycosylation
Severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS)
coronaviruses (CoVs) are zoonotic pathogens with high fatality rates and pandemic …
coronaviruses (CoVs) are zoonotic pathogens with high fatality rates and pandemic …
Signatures of immune selection in intact and defective proviruses distinguish HIV-1 elite controllers
Increasing evidence suggests that durable drug-free control of HIV-1 replication is enabled
by effective cellular immune responses that may induce an attenuated viral reservoir …
by effective cellular immune responses that may induce an attenuated viral reservoir …
A predictive fitness model for influenza
M Łuksza, M Lässig - Nature, 2014 - nature.com
The seasonal human influenza A/H3N2 virus undergoes rapid evolution, which produces
significant year-to-year sequence turnover in the population of circulating strains. Adaptive …
significant year-to-year sequence turnover in the population of circulating strains. Adaptive …
Control of human viral infections by natural killer cells
S Jost, M Altfeld - Annual review of immunology, 2013 - annualreviews.org
Natural killer (NK) cells are effector cells of the innate immune system and are important in
the control of viral infections. Their relevance is reflected by the multiple mechanisms …
the control of viral infections. Their relevance is reflected by the multiple mechanisms …
Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120
A substantial proportion of the broadly neutralizing antibodies (bnAbs) identified in certain
HIV-infected donors recognize glycan-dependent epitopes on HIV-1 gp120. Here we …
HIV-infected donors recognize glycan-dependent epitopes on HIV-1 gp120. Here we …