Expression-system-dependent modulation of HIV-1 envelope glycoprotein antigenicity and immunogenicity

L Kong, NC Sheppard, GBE Stewart-Jones… - Journal of molecular …, 2010 - Elsevier
Recombinant expression systems differ in the type of glycosylation they impart on expressed
antigens such as the human immunodeficiency virus type 1 (HIV-1) envelope glycoproteins …

HIV-1 continues to replicate and evolve in patients with natural control of HIV infection

H Mens, M Kearney, A Wiegand, W Shao… - Journal of …, 2010 - Am Soc Microbiol
Elucidating mechanisms leading to the natural control of HIV-1 infection is of great
importance for vaccine design and for understanding viral pathogenesis. Rare HIV-1 …

High mannose-binding lectin with preference for the cluster of α1–2-mannose from the green alga Boodlea coacta is a potent entry inhibitor of HIV-1 and influenza …

Y Sato, M Hirayama, K Morimoto, N Yamamoto… - Journal of Biological …, 2011 - ASBMB
The complete amino acid sequence of a lectin from the green alga Boodlea coacta (BCA),
which was determined by a combination of Edman degradation of its peptide fragments and …

Longer V1V2 region with increased number of potential N-linked glycosylation sites in the HIV-1 envelope glycoprotein protects against HIV-specific neutralizing …

MJ van Gils, EM Bunnik, BD Boeser-Nunnink… - Journal of …, 2011 - Am Soc Microbiol
Human immunodeficiency virus type 1 (HIV-1) has the ability to adapt to the host
environment by escaping from host immune responses. We previously observed that escape …

Characterization of human endogenous retroviral elements in the blood of HIV-1-infected individuals

R Contreras-Galindo, MH Kaplan… - Journal of …, 2012 - Am Soc Microbiol
We previously reported finding the RNA of a type K human endogenous retrovirus, HERV-K
(HML-2), at high titers in the plasma of HIV-1-infected and cancer patients (R. Contreras …

Pandemic H1N1 influenza A viruses are resistant to the antiviral activities of innate immune proteins of the collectin and pentraxin superfamilies

ER Job, YM Deng, MD Tate, B Bottazzi… - The Journal of …, 2010 - journals.aai.org
Acquired immune responses elicited to recent strains of seasonal H1N1 influenza viruses
provide limited protection against emerging A (H1N1) pandemic viruses. Accordingly, pre …

[HTML][HTML] Human influenza virus hemagglutinins contain conserved oligomannose N-linked glycans allowing potent neutralization by lectins

AJ Thompson, L Cao, Y Ma, X Wang, JK Diedrich… - Cell Host & Microbe, 2020 - cell.com
Hemagglutinins (HAs) from human influenza viruses adapt to bind α2-6-linked sialosides,
overcoming a receptor-defined species barrier distinct from the α2-3 specificity of avian virus …

Cell surface glycan–lectin interactions in tumor metastasis

NDS Rambaruth, MV Dwek - Acta histochemica, 2011 - Elsevier
The development of secondary cancers, metastases, requires that a multitude of events are
completed in an ordered and sequential manner. This review focuses on the role of cell …

Microsecond dynamics control the HIV-1 envelope conformation

AL Bennett, R Edwards, I Kosheleva, C Saunders… - Science …, 2024 - science.org
The HIV-1 Envelope (Env) glycoprotein facilitates host cell fusion through a complex series
of receptor-induced structural changes. Although remarkable progress has been made in …

High mannose-specific lectin (KAA-2) from the red alga Kappaphycus alvarezii potently inhibits influenza virus infection in a strain-independent manner

Y Sato, K Morimoto, M Hirayama, K Hori - Biochemical and biophysical …, 2011 - Elsevier
The carbohydrate binding profile of the red algal lectin KAA-2 from Kappaphycus alvarezii
was evaluated by a centrifugal ultrafiltration–HPLC method using pyridylaminated …