BET epigenetic reader proteins in cardiovascular transcriptional programs
Epigenetic mechanisms involve the placing (writing) or removal (erasing) of histone
modifications that allow heterochromatin to transition to the open, activated euchromatin …
modifications that allow heterochromatin to transition to the open, activated euchromatin …
Epigenetics and pulmonary diseases in the horizon of precision medicine: a review
Epigenetic mechanisms represent potential molecular routes which could bridge the gap
between genetic background and environmental risk factors contributing to the …
between genetic background and environmental risk factors contributing to the …
[HTML][HTML] Multiple-ancestry genome-wide association study identifies 27 loci associated with measures of hemolysis following blood storage
Background The evolutionary pressure of endemic malaria and other erythrocytic pathogens
has shaped variation in genes encoding erythrocyte structural and functional proteins …
has shaped variation in genes encoding erythrocyte structural and functional proteins …
[HTML][HTML] Individualized interactomes for network-based precision medicine in hypertrophic cardiomyopathy with implications for other clinical pathophenotypes
Progress in precision medicine is limited by insufficient knowledge of transcriptomic or
proteomic features in involved tissues that define pathobiological differences between …
proteomic features in involved tissues that define pathobiological differences between …
Multiomics network medicine approaches to precision medicine and therapeutics in cardiovascular diseases
Cardiovascular diseases (CVD) are the leading cause of death worldwide and display
complex phenotypic heterogeneity caused by many convergent processes, including …
complex phenotypic heterogeneity caused by many convergent processes, including …
[HTML][HTML] Clinical epigenetics settings for cancer and cardiovascular diseases: real-life applications of network medicine at the bedside
Despite impressive efforts invested in epigenetic research in the last 50 years, clinical
applications are still lacking. Only a few university hospital centers currently use epigenetic …
applications are still lacking. Only a few university hospital centers currently use epigenetic …
[HTML][HTML] Artificial intelligence and precision medicine: A new frontier for the treatment of brain tumors
AK Philip, BA Samuel, S Bhatia, SAM Khalifa… - Life, 2022 - mdpi.com
Brain tumors are a widespread and serious neurological phenomenon that can be life-
threatening. The computing field has allowed for the development of artificial intelligence …
threatening. The computing field has allowed for the development of artificial intelligence …
Harnessing big data to advance treatment and understanding of pulmonary hypertension
Pulmonary hypertension is a complex disease with multiple causes, corresponding to
phenotypic heterogeneity and variable therapeutic responses. Advancing understanding of …
phenotypic heterogeneity and variable therapeutic responses. Advancing understanding of …
[HTML][HTML] Functional mutation, splice, distribution, and divergence analysis of impactful genes associated with heart failure and other cardiovascular diseases
I Mhatre, H Abdelhalim, W Degroat, S Ashok… - Scientific reports, 2023 - nature.com
Cardiovascular disease (CVD) is caused by a multitude of complex and largely heritable
conditions. Identifying key genes and understanding their susceptibility to CVD in the human …
conditions. Identifying key genes and understanding their susceptibility to CVD in the human …
[PDF][PDF] Big data and predictive analytics in healthcare in Bangladesh: regulatory challenges
Big data analytics and artificial intelligence are revolutionizing the global healthcare
industry. As the world accumulates unfathomable volumes of data and health technology …
industry. As the world accumulates unfathomable volumes of data and health technology …