Phagocytosis of haemozoin (malarial pigment) enhances metalloproteinase-9 activity in human adherent monocytes: role of IL-1beta and 15-HETE

M Prato, V Gallo, G Giribaldi, P Arese - Malaria Journal, 2008 - Springer
Background It has been shown previously that human monocytes fed with haemozoin (HZ)
or trophozoite-parasitized RBCs displayed increased matrix metalloproteinase-9 (MMP-9) …

Polyphenols from Chilean propolis and pinocembrin reduce MMP‐9 gene expression and activity in activated macrophages

N Saavedra, A Cuevas, MF Cavalcante… - BioMed Research …, 2016 - Wiley Online Library
Polyphenols from diverse sources have shown anti‐inflammatory activity. In the context of
atherosclerosis, macrophages play important roles including matrix metalloproteinases …

PARP-1 inhibition provides protection against elastase-induced emphysema by mitigating the expression of matrix metalloproteinases

V Dharwal, R Sandhir, AS Naura - Molecular and Cellular Biochemistry, 2019 - Springer
In our previous study, we have shown that PARP-1 inhibition (genetic or pharmacological)
ameliorates elastase-induced inflammation and emphysema. Since matrix …

Anti-inflammatory activity of mulberrofuran K isolated from the bark of Morus bombycis

SY Shim, SH Sung, M Lee - International Immunopharmacology, 2018 - Elsevier
Morus bombycis Koidzumi, commonly known as silkworm mulberry, is a plant belonging to
family Moraceae. It has been used in Asian countries as a traditional medicine for treating …

Aspirin suppresses TNF‑α‑induced MMP‑9 expression via NF‑κB and MAPK signaling pathways in RAW264. 7 cells

P Zhang, C Wu, XH Huang… - Experimental and …, 2017 - spandidos-publications.com
Numerous studies have indicated that the expression of matrix metalloproteinase‑9 (MMP‑9)
contributes to the atherosclerotic plaque hemorrhage and rupture. Aspirin, a non‑steroidal …

The vertebrate homologue of sulfide-quinone reductase in mammalian mitochondria

M Ackermann, M Kubitza, G Hauska, AL Piña - Cell and tissue research, 2014 - Springer
Hydrogen sulfide (H 2 S) is the first inorganic compound identified as both a substrate for
mitochondrial oxidative phosphorylation and a transmitter in mammalian cells. H 2 S seems …

l-Menthol alleviates cigarette smoke extract induced lung injury in rats by inhibiting oxidative stress and inflammation via nuclear factor kappa B, p38 MAPK and Nrf2 …

Y Liu, A Li, X Feng, X Jiang, X Sun, W Huang, X Zhu… - RSC …, 2018 - pubs.rsc.org
L-Menthol is the main ingredient of peppermint which affects various pharmacological
effects such as anti-inflammation and anti-oxidative activity. In this study, we aimed to …

Role of MMPs in orchestrating inflammatory response in human monocytes via a TREM-1-PI3K-NF-κB pathway

V Gómez-Piña, E Martínez… - Journal of Leukocyte …, 2012 - academic.oup.com
The MMPs constitute a family of endopeptidases that can cleavage extracellular proteins.
They are involved in a number of events; some of these include inflammatory processes …

Regulatory impact of statins on macrophage polarization: mechanistic and therapeutic implications

M Sadeghi, S Khayati, S Dehnavi… - Journal of Pharmacy …, 2024 - academic.oup.com
Statins, also known as HMG-CoA reductase inhibitors, are widely prescribed drugs for the
prevention and treatment of cardiovascular diseases. In addition to their lipid-lowering …

[HTML][HTML] Tempol relieves lung injury in a rat model of chronic intermittent hypoxia via suppression of inflammation and oxidative stress

Y Wang, B Hai, L Ai, Y Cao, R Li, H Li… - Iranian journal of basic …, 2018 - ncbi.nlm.nih.gov
Objective (s): Obstructive sleep apnea (OSA) is confirmed to cause lesions in multiple
organs, especially in the lung tissue. Tempol is an antioxidant that has been reported to …