Skin aging is a multi-factorial process that affects nearly every aspect of skin biology and
function. With age, an impairment of structures, quality characteristics, and functions of the …

Skin aging is a multi-factorial process that affects nearly every aspect of skin biology and
function. The processes developing in the skin during aging are based on fundamental …

Mechanistic insight into ageing may empower prolonging the lifespan of humans; however,
a complete understanding of this process is still lacking despite a plethora of ageing …

Insulin/IGF-1-like signaling (IIS) plays a crucial, conserved role in development, growth,
reproduction, stress tolerance, and longevity. In Caenorhabditis elegans, the enhanced …

Well-known theories of aging suggest that a certain metabolic defect negatively affects vital
activity of the cell, be it oxidative stress, the accumulation of lesions in DNA, the exhaustion …

Aging is the most prominent risk factor for many diseases, which is considered to be a
complicated biological process. The rate of aging depends on the effectiveness of important …

Maintenance of active longevity, preservation of physical activity, and prevention of
decreased mobility associated with injury or age of patients are among the most urgent tasks …

Histone acetyltransferases of the CBP/p300 family are involved in transcriptional regulation
and many biological processes (cell proliferation and differentiation, development, and …

Aging is a natural process of extinction of the body and the main aspect that determines the
life expectancy for individuals who have survived to the post-reproductive period. The …

The transcriptional coactivators Yes-associated protein (YAP) and transcriptional coactivator
with PDZ-binding motif (TAZ) are the main downstream effectors of the evolutionarily …